Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | FPR3 | P25089 | 3/20 | 0.37 |
| ▸ | FPR2 | P25090 | 3/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4979553 | 0.93 | CYP1A2 (0.44) | KDM4EALDH1A1CYP1A2FPR3FPR2 | |
| SCHEMBL4979942 | 0.89 | MGLL (0.38) | ALDH1A1SLC1A3SLC1A2SLC1A1HPGD | |
| SCHEMBL3982025 | 0.88 | MGLL (0.42) | ALDH1A1FPR3FPR2SLC1A3SLC1A2 | |
| SCHEMBL4984400 | 0.88 | MGLL (0.42) | ALDH1A1FPR3FPR2SLC1A3SLC1A2 | |
| SCHEMBL3977113 | 0.88 | MGLL (0.42) | ALDH1A1FPR3FPR2SLC1A3SLC1A2 | |
| SCHEMBL4979475 | 0.88 | MGLL (0.42) | ALDH1A1FPR3FPR2SLC1A3SLC1A2 | |
| SCHEMBL4979173 | 0.86 | NAMPT (0.40) | CYP1A2L3MBTL1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL4980961 | 0.86 | LMNA (0.42) | KDM4EALDH1A1FPR3FPR2SLC1A3 | |
| SCHEMBL4983200 | 0.85 | LMNA (0.43) | KDM4EALDH1A1L3MBTL1FPR3FPR2 | |
| SCHEMBL4980233 | 0.84 | SLC1A3 (0.40) | KDM4ECYP1A2SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096875-A1 | THIOUREA COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096875-A1 | THIOUREA COMPOUNDS | TPMT, HAVCR2, ETV6 | KDM4E 1989/4885ALDH1A1 820/4885CYP1A2 555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.