SCHEMBL4979755

SCHEMBL4979755

O=C1C(c2ccccc2)=C2C(=C1c1ccccc1)c1c3ccccc3cc3cccc2c13

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.60
ALOX5 P09917 1/20 0.40
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
GPR84 Q9NQS5 3/20 0.38
KDM4E B2RXH2 2/20 0.38
DNMT1 P26358 1/20 0.38
ALDH1A1 P00352 4/20 0.37
HPGD P15428 3/20 0.37
MAOA P21397 2/20 0.37
ERBB2 P04626 1/20 0.37
CYP1A2 P05177 1/20 0.37
FYN P06241 1/20 0.37
ACHE P22303 1/20 0.37
AHR P35869 1/20 0.37
TSHR P16473 1/20 0.37
MAPK1 P28482 1/20 0.37
CASP1 P29466 1/20 0.37
HIF1A Q16665 1/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10304455 0.82 ALDH1A1 (0.54) CES1ALOX5MEN1KMT2AGPR84
SCHEMBL75606 0.79 ALDH1A1 (0.56) CES1MEN1KMT2AKDM4EDNMT1
SCHEMBL29773784 0.79 ALDH1A1 (0.56) CES1MEN1KMT2AKDM4EDNMT1
SCHEMBL14680387 0.77 PTPN1 (0.41) CES1MEN1KMT2AKDM4EDNMT1
SCHEMBL21889361 0.77 ALDH1A1 (0.44) CES1ALOX5MEN1KMT2AKDM4E
SCHEMBL2519749 0.76 CES1 (0.59) CES1ALOX5MEN1KMT2AGPR84
SCHEMBL2156357 0.76 CES1 (1.00) CES1MEN1KMT2AGPR84KDM4E
SCHEMBL579274 0.76 CES1 (1.00) CES1MEN1KMT2AGPR84KDM4E
SCHEMBL12179530 0.76 P2RX7 (0.37) CES1MEN1KMT2AALDH1A1L3MBTL1
SCHEMBL17034792 0.74 CES1 (0.57) CES1ALOX5MEN1KMT2AGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080074045-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2008-03-27 US disclosed
EP-1138745-B1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO (JP) 2007-03-28 EP disclosed
EP-1757670-A2 Organic electroluminescent element IDEMITSU KOSAN COMPANY LIMITED (JP) 2007-02-28 EP disclosed
US-20070003788-A1 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2007-01-04 US disclosed
US-20060024523-A1 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2006-02-02 US disclosed
US-6818327-B2 COLOR PURITY, EFFICIENCY IDEMITSU KOSAN CO., LTD. (JP) 2004-11-16 US disclosed
US-6815090-B1 ACENAPTHO(1,2-K)FLUORANTHENE DERIVATIVES; COLOR PURITY, EFFICIENT LIGHT EMISSION, DURABILITY IDEMITSU KOSAN CO., LTD. (JP) 2004-11-09 US disclosed
US-20040214043-A1 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2004-10-28 US disclosed
US-20030054200-A1 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2003-03-20 US disclosed
EP-1138745-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN COMPANY LIMITED (JP) 2001-10-04 EP disclosed