Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.43 |
| ▸ | GALR1 | P47211 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28753798 | 0.98 | NISCH (0.42) | NISCHGALR1ALDH1A1CYP2A6TSHR | |
| SCHEMBL1783499 | 0.98 | NISCH (0.42) | NISCHGALR1ALDH1A1CYP2A6TSHR | |
| SCHEMBL4723266 | 0.95 | NISCH (0.43) | NISCHGALR1ALDH1A1CYP2A6TSHR | |
| SCHEMBL497769 | 0.91 | ALDH1A1 (0.46) | NISCHGALR1ALDH1A1CYP2A6TSHR | |
| SCHEMBL9044714 | 0.81 | NISCH (0.47) | NISCHALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL4722083 | 0.81 | ALDH1A1 (0.39) | ALDH1A1TSHRHSD17B10KDM4EGAA | |
| SCHEMBL4721549 | 0.79 | ALDH1A1 (0.38) | ALDH1A1TSHRHSD17B10KDM4EGAA | |
| SCHEMBL29186323 | 0.77 | NISCH (0.43) | NISCHGALR1ALDH1A1CYP2A6TSHR | |
| SCHEMBL25302086 | 0.77 | ALDH1A1 (0.59) | NISCHALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL29350007 | 0.77 | ALDH1A1 (0.59) | NISCHALDH1A1CYP2A6TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654225-A4 | MELANIN CONCENTRATING HORMONE RECEPTOR ANTAGONISTS | AMGEN INC (US) | 2007-11-28 | — | — | EP | claimed |
| EP-1654225-A2 | MELANIN CONCENTRATING HORMONE RECEPTOR ANTAGONISTS | Amgen, Inc. (US) | 2006-05-10 | — | — | EP | claimed |
| US-20050256161-A1 | Melanin concentrating hormone receptor antagonists | AMGEN INC. | 2005-11-17 | — | — | US | claimed |
| WO-2005019240-A2 | MELANIN CONCENTRATING HORMONE RECEPTOR ANTAGONISTS | AMGEN, INC. (US) | 2005-03-03 | — | — | WO | claimed |
| CN-115101700-A | Organic electroluminescent device | 长春海谱润斯科技股份有限公司 | 2022-09-23 | — | — | CN | disclosed |
| CN-114665049-A | Organic electroluminescent device | 长春海谱润斯科技股份有限公司 | 2022-06-24 | — | — | CN | disclosed |
| CN-114573536-A | Star triarylamine derivative and organic electroluminescent device thereof | 长春海谱润斯科技股份有限公司 | 2022-06-03 | — | — | CN | disclosed |
| EP-2796562-A1 | METHOD FOR PRODUCING OPTICALLY-ACTIVE -SUBSTITUTED- -AMINO ACID | Sumitomo Chemical Co., Ltd (JP) | 2014-10-29 | — | — | EP | disclosed |
| CN-103998421-A | Racemization method of alpha-substituted-beta-amino acid ester | SUMITOMO CHEMICAL CO | 2014-08-20 | — | — | CN | disclosed |
| CN-103998618-A | Process for producing optically active alpha-substituted beta-amino acid | SUMITOMO CHEMICAL CO | 2014-08-20 | — | — | CN | disclosed |
| US-20130177963-A1 | ASYMMETRIC HYDROLASE AND GENE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-07-11 | — | — | US | disclosed |
| EP-2607480-A1 | Asymmetric hydrolase and gene thereof | Sumitomo Chemical Company, Limited (JP) | 2013-06-26 | — | — | EP | disclosed |
| WO-2006079916-A1 | THIENO [2,3-D] PYRIMIDINE COMPOUNDS AS INHIBITORS OF ADP-MEDIATED PLATELETS AGGREGATION | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-08-03 | — | — | WO | disclosed |
| EP-1654225-A2 | MELANIN CONCENTRATING HORMONE RECEPTOR ANTAGONISTS | Amgen, Inc. (US) | 2006-05-10 | — | — | EP | disclosed |
| US-20050256161-A1 | Melanin concentrating hormone receptor antagonists | AMGEN INC. | 2005-11-17 | — | — | US | disclosed |
| CN-1644640-A | Compositions and methods for controlled polishing of copper | CMP ROHM AND HAAS ELECTRONIC M (US) | 2005-07-27 | — | — | CN | disclosed |
| US-20050136670-A1 | Compositions and methods for controlled polishing of copper | ROHM AND HAAS ELECTRONIC MATERIALS CMP HOLDINGS, INC. | 2005-06-23 | — | — | US | disclosed |
| WO-2005019240-A2 | MELANIN CONCENTRATING HORMONE RECEPTOR ANTAGONISTS | AMGEN, INC. (US) | 2005-03-03 | — | — | WO | disclosed |
| US-20040067436-A1 | Polymerizable silicon-containing compound, manufacturing method, polymer, resist composition and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2004-04-08 | — | — | US | disclosed |
| US-6649768-B1 | Converting, in dimethyl sulfoxide, 3-haloacetylpyridine to glyoxal compound, reacting with ammonia and aldehyde to produce 3-(4-imidazolyl)pyridine compound | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2003-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256161-A1 | Melanin concentrating hormone receptor antagonists | MCHR1, MC1R, NPY1R | NISCH 1322/4885GALR1 28/4885ALDH1A1 1836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.