Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GALR1 | P47211 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL497993 | 0.91 | NISCH (0.43) | ALDH1A1TSHRHSD17B10CYP2A6TDP1 | |
| SCHEMBL4723266 | 0.91 | NISCH (0.43) | ALDH1A1TSHRHSD17B10CYP2A6TDP1 | |
| SCHEMBL28753798 | 0.89 | NISCH (0.42) | ALDH1A1TSHRHSD17B10CYP2A6TDP1 | |
| SCHEMBL1783499 | 0.89 | NISCH (0.42) | ALDH1A1TSHRHSD17B10CYP2A6TDP1 | |
| SCHEMBL9044714 | 0.85 | NISCH (0.47) | ALDH1A1TSHRHSD17B10CYP2A6TDP1 | |
| SCHEMBL31447766 | 0.84 | ALDH1A1 (0.56) | ALDH1A1TSHRHSD17B10CYP2A6TDP1 | |
| SCHEMBL25302086 | 0.81 | ALDH1A1 (0.59) | ALDH1A1TSHRHSD17B10CYP2A6TDP1 | |
| SCHEMBL27953 | 0.81 | ALDH1A1 (0.59) | ALDH1A1TSHRHSD17B10CYP2A6TDP1 | |
| SCHEMBL29350007 | 0.81 | ALDH1A1 (0.59) | ALDH1A1TSHRHSD17B10CYP2A6TDP1 | |
| SCHEMBL4723992 | 0.79 | ALDH1A1 (0.41) | ALDH1A1TSHRHSD17B10TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4165033-A1 | SHP2 INHIBITORS, COMPOSITIONS AND USES THEREOF | Betta Pharmaceuticals Co., Ltd (CN) | 2023-04-19 | — | — | EP | claimed |
| WO-2021249449-A1 | SHP2 INHIBITORS, COMPOSITIONS AND USES THEREOF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2021-12-16 | — | — | WO | claimed |
| CN-104974206-B | The Phosphoramidate derivatives of FdUrd for treating cancer | 努卡那生物医药有限责任公司 | 2019-08-23 | — | — | CN | claimed |
| EP-1654225-A4 | MELANIN CONCENTRATING HORMONE RECEPTOR ANTAGONISTS | AMGEN INC (US) | 2007-11-28 | — | — | EP | claimed |
| EP-1654225-A2 | MELANIN CONCENTRATING HORMONE RECEPTOR ANTAGONISTS | Amgen, Inc. (US) | 2006-05-10 | — | — | EP | claimed |
| US-20050256161-A1 | Melanin concentrating hormone receptor antagonists | AMGEN INC. | 2005-11-17 | — | — | US | claimed |
| WO-2005019240-A2 | MELANIN CONCENTRATING HORMONE RECEPTOR ANTAGONISTS | AMGEN, INC. (US) | 2005-03-03 | — | — | WO | claimed |
| CN-114944459-B | Organic electroluminescent device | 长春海谱润斯科技股份有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-118139509-A | Organic electroluminescent device | 长春海谱润斯科技股份有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-117924268-A | Heterocyclic compound and organic electroluminescent device thereof | 长春海谱润斯科技股份有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-117903189-A | Carbazole compound and organic electroluminescent device thereof | 长春海谱润斯科技股份有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-117903188-A | Heterocyclic compound and organic electroluminescent device thereof | 长春海谱润斯科技股份有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-117756648-A | Aromatic amine compound and organic electroluminescent device thereof | 长春海谱润斯科技股份有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-1213379-A | Peptide derivatives | ZENECA LTD (GB) | 1999-04-07 | — | — | CN | disclosed |
| EP-0882066-A1 | PEPTIDE DERIVATIVES | ZENECA LIMITED (GB) | 1998-12-09 | — | — | EP | disclosed |
| WO-1998025951-A1 | INHIBITORS OF PEPTIDE BINDING TO MHC CLASS II PROTEINS | ZENECA LIMITED (GB) | 1998-06-18 | — | — | WO | disclosed |
| WO-1998023644-A1 | PEPTIDE DERIVATIVES | ZENECA LIMITED (GB) | 1998-06-04 | — | — | WO | disclosed |
| WO-1998017680-A1 | PEPTIDE ANALOGUES CONTAINING A 7-MEMBERED LACTAM RING | ZENECA LIMITED (GB) | 1998-04-30 | — | — | WO | disclosed |
| WO-1997046578-A1 | PEPTIDE DERIVATIVES | ZENECA LIMITED (GB) | 1997-12-11 | — | — | WO | disclosed |
| WO-1997031023-A1 | PEPTIDE DERIVATIVES | ZENECA LIMITED (GB) | 1997-08-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256161-A1 | Melanin concentrating hormone receptor antagonists | MCHR1, MC1R, NPY1R | ALDH1A1 1836/4885TSHR 19/4885HSD17B10 1382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.