Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.42 |
| ▸ | GALR1 | P47211 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28753798 | 1.00 | NISCH (0.42) | NISCHGALR1ALDH1A1CYP2A6TSHR | |
| SCHEMBL497993 | 0.98 | NISCH (0.43) | NISCHGALR1ALDH1A1CYP2A6TSHR | |
| SCHEMBL4723266 | 0.93 | NISCH (0.43) | NISCHGALR1ALDH1A1CYP2A6TSHR | |
| SCHEMBL497769 | 0.89 | ALDH1A1 (0.46) | NISCHGALR1ALDH1A1CYP2A6TSHR | |
| SCHEMBL4721549 | 0.82 | ALDH1A1 (0.38) | ALDH1A1TSHRHSD17B10KDM4EGAA | |
| SCHEMBL29109615 | 0.80 | ALDH1A1 (0.37) | ALDH1A1TSHRHSD17B10TDP1KDM4E | |
| SCHEMBL9044714 | 0.79 | NISCH (0.47) | NISCHALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL4722083 | 0.79 | ALDH1A1 (0.39) | ALDH1A1TSHRHSD17B10KDM4EGAA | |
| SCHEMBL29110070 | 0.78 | ALDH1A1 (0.38) | ALDH1A1TSHRHSD17B10TDP1KDM4E | |
| SCHEMBL29186323 | 0.76 | NISCH (0.43) | NISCHGALR1ALDH1A1CYP2A6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115424682-A | Ethylene oligomerization catalyst molecule design method based on machine learning | 华东理工大学 | 2022-12-02 | — | — | CN | claimed |
| CN-114621181-A | Star-shaped tetramine derivative and organic electroluminescent device thereof | 长春海谱润斯科技股份有限公司 | 2022-06-14 | — | — | CN | claimed |
| US-11021501-B2 | Creatine phosphate analog prodrugs, compositions and methods of use thereof | Farmington Pharma Development (US) | 2021-06-01 | — | — | US | claimed |
| CN-108516919-A | A kind of preparation method of the cyclohexyl derivative of naphthalene | 吉林化工学院 | 2018-09-11 | — | — | CN | claimed |
| WO-2016160885-A1 | CREATINE PHOSPHATE ANALOG PRODRUGS, COMPOSITIONS AND USES THEREOF | Farmington Pharma Development (US) | 2016-10-06 | — | — | WO | claimed |
| US-20160289253-A1 | CREATINE PHOSPHATE ANALOG PRODRUGS, COMPOSITIONS AND METHODS OF USE THEREOF | Farmington Pharma Development | 2016-10-06 | — | — | US | claimed |
| CN-104511311-A | High-selectivity catalyst system used in trimerization and tetramerization of ethylene and use method thereof | UNIV EAST CHINA SCIENCE & TECH | 2015-04-15 | — | — | CN | claimed |
| US-8466131-B2 | Ligands specific for cannabinoid receptor subtype 2 | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2013-06-18 | — | — | US | claimed |
| US-20110118214-A1 | LIGANDS SPECIFIC FOR CANNABINOID RECEPTOR SUBTYPE 2 | University of Pittsburgh--Of the Commonwealth | 2011-05-19 | — | — | US | claimed |
| WO-2009058377-A1 | LIGANDS SPECIFIC FOR CANNABINOID RECEPTOR SUBTYPE 2 | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2009-05-07 | — | — | WO | claimed |
| EP-1654225-A4 | MELANIN CONCENTRATING HORMONE RECEPTOR ANTAGONISTS | AMGEN INC (US) | 2007-11-28 | — | — | EP | claimed |
| EP-1654225-A2 | MELANIN CONCENTRATING HORMONE RECEPTOR ANTAGONISTS | Amgen, Inc. (US) | 2006-05-10 | — | — | EP | claimed |
| US-20050256161-A1 | Melanin concentrating hormone receptor antagonists | AMGEN INC. | 2005-11-17 | — | — | US | claimed |
| WO-2005019240-A2 | MELANIN CONCENTRATING HORMONE RECEPTOR ANTAGONISTS | AMGEN, INC. (US) | 2005-03-03 | — | — | WO | claimed |
| CN-114573536-B | Star-shaped triarylamine derivative and organic electroluminescent device thereof | 长春海谱润斯科技股份有限公司 | 2023-12-22 | — | — | CN | disclosed |
| EP-4284853-A1 | ADDUCT OF ALKYLATED DIAMINE AND EPOXY NOVOLAC RESIN | Sika Technology AG (CH) | 2023-12-06 | — | — | EP | disclosed |
| US-11807656-B2 | Polycyclic aromatic compound and light emission layer-forming composition | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2023-11-07 | — | — | US | disclosed |
| US-4031023-A | Lubricating compositions and methods utilizing hydroxy thioethers | THE LUBRIZOL CORPORATION (US) | 1977-06-21 | — | — | US | disclosed |
| US-4029615-A | AZO COMPOUNDS | PENNWALT CORPORATION (US) | 1977-06-14 | — | — | US | disclosed |
| US-3993609-A | ACID SENSITIVE AZO PROMOTERS | PENNWALT CORPORATION (US) | 1976-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11807656-B2 | Polycyclic aromatic compound and light emission layer-forming composition | ARNT, TYR, NLRP3 | NISCH 2456/4885GALR1 316/4885ALDH1A1 2119/4885 |
| US-20110118214-A1 | LIGANDS SPECIFIC FOR CANNABINOID RECEPTOR SUBTYPE 2 | CNR1, CNR2, OPRL1 | NISCH 2997/4885GALR1 25/4885ALDH1A1 3035/4885 |
| US-20160289253-A1 | CREATINE PHOSPHATE ANALOG PRODRUGS, COMPOSITIONS AND METHODS OF USE THEREOF | CKMT1A; CKMT1B, SLC2A1, SLC2A4 | NISCH 2839/4885GALR1 3917/4885ALDH1A1 2325/4885 |
| US-20050256161-A1 | Melanin concentrating hormone receptor antagonists | MCHR1, MC1R, NPY1R | NISCH 1322/4885GALR1 28/4885ALDH1A1 1836/4885 |
| US-11021501-B2 | Creatine phosphate analog prodrugs, compositions and methods of use thereof | CKMT1A; CKMT1B, SLC2A1, SLC2A4 | NISCH 2839/4885GALR1 3917/4885ALDH1A1 2325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.