SCHEMBL498064

SCHEMBL498064

O=C(O)C(S)S.OCc1cccc(CO)c1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
ACMSD Q8TDX5 1/20 0.45
ENPP2 Q13822 1/20 0.44
KDM4E B2RXH2 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
CYP1A2 P05177 1/20 0.42
CNR2 P34972 1/20 0.41
FFAR1 O14842 1/20 0.41
FOLH1 Q04609 3/20 0.41
CPA3 P15088 1/20 0.41
PRSS1 P07477 1/20 0.41
PRSS2 P07478 1/20 0.41
PRSS3 P35030 1/20 0.41
PPARG P37231 1/20 0.41
PPARA Q07869 1/20 0.41
ADAMTS4 O75173 1/20 0.40
PRKCI P41743 1/20 0.40
DAO P14920 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL498838 0.82 TSHR (0.48) TSHRKDM4ECYP1A2PRSS1PRSS2
SCHEMBL4329928 0.82 LDHA (0.47) TSHRACMSDCYP1A2FOLH1PPARG
SCHEMBL123838 0.79 TSHR (0.61) TSHRACMSDENPP2PRSS1PRSS2
SCHEMBL1410876 0.77 PLA2G10 (0.48) TSHRFFAR1PPARAADAMTS4
SCHEMBL1512890 0.77 SLC7A5 (0.67) KDM4E
SCHEMBL31369893 0.77 SLC7A5 (0.67) KDM4E
SCHEMBL1512888 0.77 SLC7A5 (0.67) KDM4E
SCHEMBL1401775 0.77 AKR1B1 (0.60) TSHRACMSDENPP2KDM4ECYP1A2
Propionic Acid SCHEMBL5936395 0.77 TSHR (0.48) TSHRACMSDENPP2SMN1; SMN2CNR2
Hydrochloric Acid SCHEMBL14334287 0.77 ENPP2 (0.58) TSHRACMSDENPP2PRSS1PRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2122684-B1 METHOD FOR MAKING SOLAR SUB-CELLS FROM A SOLAR CELL HYET ENERGY SYSTEMS B V (NL) 2017-02-08 EP disclosed
US-8105868-B2 Method for making solar sub-cells from a solar cell HELIANTHOS B.V. (NL) 2012-01-31 US disclosed
US-8025929-B2 Method for preparing flexible mechanically compensated transparent layered material HELIANTHOS B.V. (NL) 2011-09-27 US disclosed
US-20100087026-A1 METHOD FOR MAKING SOLAR SUB-CELLS FROM A SOLAR CELL HELIANTHOS B.V. (NL) 2010-04-08 US disclosed
EP-2122684-A2 METHOD FOR MAKING SOLAR SUB-CELLS FROM A SOLAR CELL Helianthos B.V. (NL) 2009-11-25 EP disclosed
US-20080193717-A1 Method for Preparing Flexible Mechanically Compensated Transparent Layered Material AKZO NOBEL N.V. (NL) 2008-08-14 US disclosed
WO-2008074879-A2 METHOD FOR MAKING SOLAR SUB-CELLS FROM A SOLAR CELL HELIANTHOS B.V. (NL) 2008-06-26 WO disclosed