SCHEMBL498838

SCHEMBL498838

O=C(O)C(S)S.OCc1ccc(CO)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.48
PPARG P37231 2/20 0.46
PPARA Q07869 2/20 0.46
LTA4H P09960 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
CA5A P35218 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
CA5B Q9Y2D0 1/20 0.41
KIF11 P52732 2/20 0.41
ADAMTS4 O75173 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
KDM4E B2RXH2 1/20 0.40
PRSS1 P07477 1/20 0.38
PRSS2 P07478 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL498064 0.82 TSHR (0.46) TSHRPPARGPPARAADAMTS4KDM4E
Oxalic Acid SCHEMBL30089202 0.78 TSHR (0.58) TSHRPPARGPPARALTA4HCA12
SCHEMBL2209126 0.76 SRC (0.56) TSHRPPARGPPARALTA4HCA12
SCHEMBL497819 0.76 KMT2A (0.47) TDP1CYP1A2
SCHEMBL17585418 0.75 TSHR (0.42) TSHRPPARGPPARALTA4HCA12
SCHEMBL12238390 0.75 LMNA (0.58) TSHRPPARGPPARALTA4HCA12
SCHEMBL41775 0.74 TSHR (0.67) TSHRPPARGPPARALTA4HCA12
SCHEMBL5279281 0.73 HSD17B10 (0.48) TSHRPPARGPPARACA12CA1
SCHEMBL216414 0.73 SLC7A5 (0.71) TDP1KDM4ECYP1A2
SCHEMBL5329341 0.73 PPARG (0.49) TSHRPPARGPPARACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2122684-B1 METHOD FOR MAKING SOLAR SUB-CELLS FROM A SOLAR CELL HYET ENERGY SYSTEMS B V (NL) 2017-02-08 EP disclosed
US-8105868-B2 Method for making solar sub-cells from a solar cell HELIANTHOS B.V. (NL) 2012-01-31 US disclosed
US-8025929-B2 Method for preparing flexible mechanically compensated transparent layered material HELIANTHOS B.V. (NL) 2011-09-27 US disclosed
US-20100087026-A1 METHOD FOR MAKING SOLAR SUB-CELLS FROM A SOLAR CELL HELIANTHOS B.V. (NL) 2010-04-08 US disclosed
EP-2122684-A2 METHOD FOR MAKING SOLAR SUB-CELLS FROM A SOLAR CELL Helianthos B.V. (NL) 2009-11-25 EP disclosed
US-20080193717-A1 Method for Preparing Flexible Mechanically Compensated Transparent Layered Material AKZO NOBEL N.V. (NL) 2008-08-14 US disclosed
WO-2008074879-A2 METHOD FOR MAKING SOLAR SUB-CELLS FROM A SOLAR CELL HELIANTHOS B.V. (NL) 2008-06-26 WO disclosed