Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13008914 | 0.95 | GBA1 (0.35) | EPHX2 | |
| SCHEMBL13008661 | 0.93 | GBA1 (0.38) | EPHX2 | |
| SCHEMBL9589284 | 0.93 | GBA1 (0.38) | EPHX2 | |
| SCHEMBL1002990 | 0.93 | GBA1 (0.38) | EPHX2 | |
| SCHEMBL581622 | 0.93 | GBA1 (0.38) | EPHX2 | |
| SCHEMBL3007587 | 0.93 | GBA1 (0.38) | EPHX2 | |
| SCHEMBL13008300 | 0.90 | CYP2D6 (0.31) | CYP2D6 | |
| SCHEMBL9039403 | 0.90 | CYP2D6 (0.31) | CYP2D6 | |
| SCHEMBL9041491 | 0.89 | CYP2D6 (0.31) | CYP2D6 | |
| SCHEMBL9040335 | 0.89 | CYP2D6 (0.31) | CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7361755-B2 | Transition-metal-catalyzed process for the conversion of alkenes to sterically hindered substituted n-alkoxyamines | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-04-22 | — | — | US | claimed |
| US-20050085636-A1 | Transition-metal-catalyzed process for the conversion of alkenes to sterically hindered substituted n-alkoxyamines | CIBA SPECIALTY CHEMICALS CORP. | 2005-04-21 | — | — | US | claimed |
| EP-1456173-A1 | TRANSITION-METAL-CATALYZED PROCESS FOR THE CONVERSION OF ALKENES TO STERICALLY HINDERED SUBSTITUTED N-ALKOXYAMINES | Ciba SC Holding AG (CH) | 2004-09-15 | — | — | EP | claimed |
| WO-2003053931-A1 | TRANSITION-METAL-CATALYZED PROCESS FOR THE CONVERSION OF ALKENES TO STERICALLY HINDERED SUBSTITUTED N-ALKOXYAMINES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-07-03 | — | — | WO | claimed |
| US-8471031-B2 | Process for the preparation of sterically hindered nitroxyl ethers | BASF SE (DE) | 2013-06-25 | — | — | US | disclosed |
| US-8471031-B2 | Process for the preparation of sterically hindered nitroxyl ethers | BASF SE (DE) | 2013-06-25 | — | — | US | disclosed |
| EP-2035381-B1 | PROCESS FOR THE PREPARATION OF STERICALLY HINDERED NITROXYL ETHERS | BASF SE (DE) | 2010-12-29 | — | — | EP | disclosed |
| US-20100249401-A1 | Process for the preparation of sterically hindered nitroxyl ethers | BASF SE (DE) | 2010-09-30 | — | — | US | disclosed |
| US-20100249401-A1 | Process for the preparation of sterically hindered nitroxyl ethers | BASF SE (DE) | 2010-09-30 | — | — | US | disclosed |
| US-7361755-B2 | Transition-metal-catalyzed process for the conversion of alkenes to sterically hindered substituted n-alkoxyamines | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-04-22 | — | — | US | disclosed |
| US-7361755-B2 | Transition-metal-catalyzed process for the conversion of alkenes to sterically hindered substituted n-alkoxyamines | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-04-22 | — | — | US | disclosed |
| US-7361755-B2 | Transition-metal-catalyzed process for the conversion of alkenes to sterically hindered substituted n-alkoxyamines | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-04-22 | — | — | US | disclosed |
| US-20050085636-A1 | Transition-metal-catalyzed process for the conversion of alkenes to sterically hindered substituted n-alkoxyamines | CIBA SPECIALTY CHEMICALS CORP. | 2005-04-21 | — | — | US | disclosed |
| EP-1456173-A1 | TRANSITION-METAL-CATALYZED PROCESS FOR THE CONVERSION OF ALKENES TO STERICALLY HINDERED SUBSTITUTED N-ALKOXYAMINES | Ciba SC Holding AG (CH) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003053931-A1 | TRANSITION-METAL-CATALYZED PROCESS FOR THE CONVERSION OF ALKENES TO STERICALLY HINDERED SUBSTITUTED N-ALKOXYAMINES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050085636-A1 | Transition-metal-catalyzed process for the conversion of alkenes to sterically hindered substituted n-alkoxyamines | PNMT, NNMT, TET2 | CYP2D6 674/4885MEN1 607/4885ALDH1A1 859/4885 |
| US-20100249401-A1 | Process for the preparation of sterically hindered nitroxyl ethers | PPOX, CBR1, CBR3 | CYP2D6 568/4885MEN1 4841/4885ALDH1A1 889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.