Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 4/20 | 0.61 |
| ▸ | SLC5A2 | P31639 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SSTR5 | P35346 | 6/20 | 0.43 |
| ▸ | SSTR3 | P32745 | 5/20 | 0.43 |
| ▸ | SSTR2 | P30874 | 3/20 | 0.43 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.43 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TACR2 | P21452 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.39 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28923022 | 1.00 | SLC5A1 (0.61) | SLC5A1SLC5A2CYP3A4CYP2C19SSTR5 | |
| SCHEMBL27473226 | 0.83 | SLC5A1 (0.55) | SLC5A1SLC5A2CYP3A4NPC1RAB9A | |
| SCHEMBL19731823 | 0.82 | GJB2 (0.47) | SLC5A1SLC5A2SSTR5SSTR3SSTR2 | |
| SCHEMBL10031321 | 0.80 | SLC5A1 (0.63) | SLC5A1SLC5A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL10031325 | 0.80 | SLC5A1 (0.63) | SLC5A1SLC5A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL15481400 | 0.80 | SLC6A2 (0.57) | SLC5A1SLC5A2CYP3A4NPC1RAB9A | |
| SCHEMBL18523297 | 0.80 | SLC6A2 (0.57) | SLC5A1SLC5A2CYP3A4NPC1RAB9A | |
| SCHEMBL6384333 | 0.79 | SSTR5 (0.44) | SSTR5SSTR3SSTR2SSTR1SSTR4 | |
| SCHEMBL6382377 | 0.79 | LGALS8 (0.43) | SLC5A1SLC5A2SSTR5SSTR3SSTR2 | |
| SCHEMBL27492046 | 0.77 | SLC6A2 (0.52) | SLC5A1SLC5A2LGALS8LGALS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1782828-B1 | PROGRESSION INHIBITOR FOR DISEASE ATTRIBUTED TO ABNORMAL ACCUMULATION OF LIVER FAT | KISSEI PHARMACEUTICAL (JP) | 2016-06-29 | — | — | EP | claimed |
| EP-1782828-B1 | PROGRESSION INHIBITOR FOR DISEASE ATTRIBUTED TO ABNORMAL ACCUMULATION OF LIVER FAT | KISSEI PHARMACEUTICAL (JP) | 2016-06-29 | — | — | EP | disclosed |
| US-20080045466-A1 | Progression Inhibitor For Disease Attributed To Abnormal Accumulation Of Liver Fat | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045466-A1 | Progression Inhibitor For Disease Attributed To Abnormal Accumulation Of Liver Fat | SLC10A1, SLC2A2, SLC2A1 | SLC5A1 12/4885SLC5A2 10/4885CYP3A4 2549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.