SCHEMBL4983584

SCHEMBL4983584

CCC1(CC)c2ccccc2C(CC)(CC)N1C(C)(C)C#N

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PGR P06401 2/20 0.34
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15069963 0.79 ALDH1A1 (0.32)
SCHEMBL4988111 0.76 MEN1 (0.30)
SCHEMBL9500670 0.75 PGR (0.32) PGR
SCHEMBL4988366 0.73 CYP2B6 (0.39)
SCHEMBL15071292 0.68 ALDH1A1 (0.34) PGRLMNA
SCHEMBL11016796 0.67 PGR (0.30) PGR
SCHEMBL325978 0.66 CYP1A2 (0.34) PGR
SCHEMBL29728008 0.66 CYP1A2 (0.34) PGR
SCHEMBL6872631 0.66 ALDH1A1 (0.41) PGRLMNA
SCHEMBL9502865 0.66 PGR (0.34) PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7388052-B2 Process for the preparation of block copolymers POLIMERI EUROPA S.P.A. (IT) 2008-06-17 US claimed
EP-1519970-B1 PROCESS FOR THE PREPARATION OF BLOCK COPOLYMERS POLIMERI EUROPA SPA (IT) 2007-10-24 EP claimed
US-20070219329-A1 polymerizing styrene using a nitroxy free radical catalyst, then adding methacrylonitrile; 2-methyl-2-(2,2,6,6-tetramethylpiperidin-1-yloxy)propionitrile catalyst; POLIMERI EUROPA S.P.A. (IT) 2007-09-20 US claimed
US-7388052-B2 Process for the preparation of block copolymers POLIMERI EUROPA S.P.A. (IT) 2008-06-17 US disclosed
EP-1519970-B1 PROCESS FOR THE PREPARATION OF BLOCK COPOLYMERS POLIMERI EUROPA SPA (IT) 2007-10-24 EP disclosed
US-20070219329-A1 polymerizing styrene using a nitroxy free radical catalyst, then adding methacrylonitrile; 2-methyl-2-(2,2,6,6-tetramethylpiperidin-1-yloxy)propionitrile catalyst; POLIMERI EUROPA S.P.A. (IT) 2007-09-20 US disclosed