SCHEMBL325978

SCHEMBL325978

CCC1(CC)c2ccccc2C(CC)(CC)N1O

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.34
CYP2C19 P33261 1/20 0.34
KMT2A Q03164 1/20 0.34
ALDH1A1 P00352 1/20 0.33
KDM4E B2RXH2 1/20 0.33
HPGD P15428 1/20 0.33
ELANE P08246 2/20 0.32
KDM1A O60341 6/20 0.31
MAOA P21397 6/20 0.31
MAOB P27338 6/20 0.31
PKM P14618 1/20 0.31
CNR1 P21554 1/20 0.31
GPR55 Q9Y2T6 1/20 0.31
PGR P06401 1/20 0.30
HDAC4 P56524 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29728008 1.00 CYP1A2 (0.34) CYP1A2CYP2C19KMT2AALDH1A1KDM4E
SCHEMBL10901108 0.82 KDM1A (0.35) CYP1A2CYP2C19KMT2AKDM4EKDM1A
SCHEMBL15071292 0.78 ALDH1A1 (0.34) CYP1A2CYP2C19KMT2AALDH1A1ELANE
SCHEMBL6872631 0.76 ALDH1A1 (0.41) CYP1A2CYP2C19KMT2AALDH1A1KDM4E
SCHEMBL15069963 0.73 ALDH1A1 (0.32) ALDH1A1ELANE
SCHEMBL18217969 0.73 PKM (0.33) ALDH1A1ELANEPKM
SCHEMBL1297947 0.70 ELANE (0.46) CYP2C19ALDH1A1ELANE
SCHEMBL564222 0.69 NOTUM (0.36) KMT2AALDH1A1KDM4EHPGD
SCHEMBL12106926 0.69 RXRA (0.33) KMT2AALDH1A1KDM4EMAOAMAOB
SCHEMBL4988366 0.67 CYP2B6 (0.39) CYP2C19ALDH1A1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3458522-B1 PROCESS FOR THE PREPARATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS HAVING A HIGH DEGREE OF PURITY ICROM SPA (IT) 2024-01-03 EP claimed
US-10723710-B2 Process for the preparation of diaminophenothiazinium compounds having a high degree of purity ICROM S.P.A. (IT) 2020-07-28 US claimed
US-20190185440-A1 PROCESS FOR THE PREPARATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS HAVING A HIGH DEGREE OF PURITY ICROM S.P.A. (IT) 2019-06-20 US claimed
US-9856364-B2 Stabilized reversible polymer composition XEROX CORPORATION (US) 2018-01-02 US claimed
US-20140353549-A1 STABILIZED REVERSIBLE POLYMER COMPOSITION XEROX CORPORATION (US) 2014-12-04 US claimed
US-8349961-B2 Process for the preparation of high impact vinylaromatic (co)polymers grafted on an elastomer POLIMERI EUROPA S.P.A. (IT) 2013-01-08 US claimed
EP-0845448-B1 Inhibiting polymerization of vinyl aromatic monomers ONDEO NALCO ENERGY SERV LP (US) 2002-01-30 EP claimed
EP-0845448-A1 Inhibiting polymerization of vinyl aromatic monomers Ciba SC Holding AG (CH) 1998-06-03 EP claimed
EP-0717054-A2 Stable free radical polymerization process and thermoplastic materials produced therefrom XEROX CORPORATION (US) 1996-06-19 EP claimed
US-5449724-A Stable free radical polymerization process and thermoplastic materials produced therefrom XEROX CORPORATION (US) 1995-09-12 US claimed
US-20240117121-A1 MULTIFUNCTIONAL NITROXIDE-MEDIATED POLYMERIZATION INITIATORS AND MULTI-ARMED POLYMERS AND HYDROGELS FORMED THEREFROM BOSTON SCIENTIFIC SCIMED, INC. (US) 2024-04-11 US disclosed
EP-3458522-B1 PROCESS FOR THE PREPARATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS HAVING A HIGH DEGREE OF PURITY ICROM SPA (IT) 2024-01-03 EP disclosed
US-11820868-B2 Multifunctional nitroxide-mediated polymerization initiators and multi-armed polymers and hydrogels formed therefrom BOSTON SCIENTIFIC SCIMED, INC. (US) 2023-11-21 US disclosed
US-11814336-B2 Oligomeric alkoxy amines ARKEMA FRANCE (FR) 2023-11-14 US disclosed
US-20210139415-A1 OLIGOMERIC ALKOXYAMINES ARKEMA FRANCE (FR) 2021-05-13 US disclosed
EP-0717054-A2 Stable free radical polymerization process and thermoplastic materials produced therefrom XEROX CORPORATION (US) 1996-06-19 EP disclosed
US-5449724-A Stable free radical polymerization process and thermoplastic materials produced therefrom XEROX CORPORATION (US) 1995-09-12 US disclosed
EP-0135280-B1 NEW POLYMERIZATION PROCESS AND POLYMERS PRODUCED THEREBY COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1993-05-12 EP disclosed
US-4581429-A Polymerization process and polymers produced thereby COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) 1986-04-08 US disclosed
EP-0135280-A2 New polymerization process and polymers produced thereby COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1985-03-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10723710-B2 Process for the preparation of diaminophenothiazinium compounds having a high degree of purity DDT, QDPR, DDC CYP1A2 545/4885CYP2C19 247/4885KMT2A 961/4885
US-20210139415-A1 OLIGOMERIC ALKOXYAMINES ALKBH3, ALK, ALKBH2 CYP1A2 2104/4885CYP2C19 3918/4885KMT2A 399/4885
US-11814336-B2 Oligomeric alkoxy amines ALKBH3, ALK, PNMT CYP1A2 1882/4885CYP2C19 3722/4885KMT2A 439/4885
US-20190185440-A1 PROCESS FOR THE PREPARATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS HAVING A HIGH DEGREE OF PURITY DDT, QDPR, DDC CYP1A2 545/4885CYP2C19 247/4885KMT2A 961/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.