SCHEMBL498388

SCHEMBL498388

COCC(C)OC(=O)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.52
POLB P06746 2/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2D6 P10635 1/20 0.52
SCN1A P35498 1/20 0.52
SCN2A Q99250 1/20 0.52
SCN3A Q9NY46 1/20 0.52
TSHR P16473 2/20 0.52
TP53 P04637 1/20 0.52
NPC1 O15118 3/20 0.51
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
PDCD1 Q15116 1/20 0.50
CD274 Q9NZQ7 1/20 0.50
ALDH1A1 P00352 3/20 0.49
RAB9A P51151 2/20 0.47
HTT P42858 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
ADRB2 P07550 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2507961 0.94 LMNA (0.48) LMNAPOLBCYP1A2CYP2D6SCN1A
SCHEMBL2182416 0.94 LMNA (0.48) LMNAPOLBCYP1A2CYP2D6SCN1A
SCHEMBL6936388 0.88 ALDH1A1 (0.52) LMNAPOLBCYP1A2CYP2D6SCN1A
SCHEMBL1255193 0.87 LMNA (0.54) LMNAPOLBCYP1A2CYP2D6SCN1A
SCHEMBL6746732 0.86 LMNA (0.50) LMNAPOLBCYP1A2CYP2D6SCN1A
SCHEMBL227395 0.86 ALDH1A1 (0.62) LMNAPOLBCYP1A2CYP2D6SCN1A
SCHEMBL16019900 0.86 ALDH1A1 (0.62) LMNAPOLBCYP1A2CYP2D6SCN1A
SCHEMBL16876662 0.85 LMNA (0.57) LMNAPOLBCYP1A2CYP2D6SCN1A
SCHEMBL16217637 0.84 ALDH1A1 (0.61) LMNAPOLBCYP1A2CYP2D6SCN1A
SCHEMBL12559135 0.84 ALDH1A1 (0.61) LMNAPOLBCYP1A2CYP2D6SCN1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12365785-B2 Glycol ether aryl ester plasticizer EASTMAN CHEMICAL COMPANY (US) 2025-07-22 US claimed
US-11718702-B2 Adhesive useful for installing vehicle windows DDP SPECIALTY ELECTRONIC MATERIALS US, LLC (US) 2023-08-08 US claimed
US-20220227962-A1 GLYCOL ETHER ARYL ESTER PLASTICIZER EASTMAN CHEMICAL COMPANY (US) 2022-07-21 US claimed
CN-110354834-B Preparation method and application of magnesium-aluminum-zirconium composite oxide catalyst 常州大学 2022-06-28 CN claimed
EP-3990532-A1 GLYCOL ETHER ARYL ESTER PLASTICIZER Eastman Chemical Company (US) 2022-05-04 EP claimed
CN-114008119-A Glycol ether aryl ester plasticizers 伊士曼化工公司 2022-02-01 CN claimed
WO-2020263593-A1 GLYCOL ETHER ARYL ESTER PLASTICIZER EASTMAN CHEMICAL COMPANY (US) 2020-12-30 WO claimed
EP-2539379-B1 AMIDE ESTER INTERNAL ELECTRON DONOR AND PROCESS W R GRACE & CO -CONN (US) 2017-09-06 EP claimed
US-9315592-B2 Process for producing procatalyst composition with alkoxyalkyl ester internal electron donor and product W. R. GRACE & CO.-CONN. (US) 2016-04-19 US claimed
US-8604146-B2 Catalyst composition with alkoxyalkyl ester internal electron donor and polymer from same DOW GLOBAL TECHNOLOGIES LLC (US) 2013-12-10 US claimed
EP-2655425-A1 PROCESS FOR PRODUCING PROCATALYST COMPOSITION WITH ALKOXYALKYL ESTER INTERNAL ELECTRON DONOR AND PRODUCT Dow Global Technologies LLC (US) 2013-10-30 EP claimed
US-20130225398-A1 Process for Producing Procatalyst Composition with Alkoxyalkyl Ester Internal Electron Donor and Product DOW GLOBAL TECHNOLOGIES LLC (US) 2013-08-29 US claimed
EP-2539379-A1 AMIDE ESTER INTERNAL ELECTRON AND PROCESS Dow Global Technologies LLC (US) 2013-01-02 EP claimed
US-20120316299-A1 Amide Ester Internal Electron Donor and Process W. R. GRACE & CO.-CONN. 2012-12-13 US claimed
WO-2012087527-A1 PROCESS FOR PRODUCING PROCATALYST COMPOSITION WITH ALKOXYALKYL ESTER INTERNAL ELECTRON DONOR AND PRODUCT DOW GLOBAL TECHNOLOGIES LLC (US) 2012-06-28 WO claimed
US-20120157295-A1 Process for Producing Procatalyst Composition with Alkoxyalkyl Ester Internal Electron Donor and Product W. R. GRACE & CO. - CONN. 2012-06-21 US claimed
WO-2011106500-A1 AMIDE ESTER INTERNAL ELECTRON AND PROCESS DOW GLOBAL TECHNOLOGIES LLC (US) 2011-09-01 WO claimed
US-4489188-A LATEX OF ADDITION POLYMER AND ETHER-ESTER SOLVENT EASTMAN KODAK COMPANY (US) 1984-12-18 US claimed
US-12552931-B2 Dihydroxy lactam based polymers, compositions and applications thereof ISP INVESTMENTS LLC (US) 2026-02-17 US disclosed
US-4489188-A LATEX OF ADDITION POLYMER AND ETHER-ESTER SOLVENT EASTMAN KODAK COMPANY (US) 1984-12-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552931-B2 Dihydroxy lactam based polymers, compositions and applications thereof PARG, GNE, PGLS LMNA 1375/4885POLB 1321/4885CYP1A2 941/4885
US-12365785-B2 Glycol ether aryl ester plasticizer DAGLA, DDT, PPARG LMNA 1384/4885POLB 2781/4885CYP1A2 741/4885
US-20220227962-A1 GLYCOL ETHER ARYL ESTER PLASTICIZER DAGLA, DDT, PPARG LMNA 1384/4885POLB 2781/4885CYP1A2 741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.