Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | WDR5 | P61964 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | CYP2E1 | P05181 | 3/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 3/20 | 0.46 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.46 |
| ▸ | ATP4A | P20648 | 5/20 | 0.45 |
| ▸ | ATP4B | P51164 | 5/20 | 0.45 |
| ▸ | ATP1A1 | P05023 | 4/20 | 0.45 |
| ▸ | ATP1B1 | P05026 | 4/20 | 0.45 |
| ▸ | ATP1A3 | P13637 | 4/20 | 0.45 |
| ▸ | ATP1B2 | P14415 | 4/20 | 0.45 |
| ▸ | ATP1A2 | P50993 | 4/20 | 0.45 |
| ▸ | ATP1B3 | P54709 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8503057 | 0.90 | CYP2C9 (0.53) | KMT2AWDR5CYP2C9CYP3A4CYP1A2 | |
| SCHEMBL9527620 | 0.90 | ATP4A (0.55) | KMT2AWDR5CYP2C9CYP3A4CYP1A2 | |
| SCHEMBL8119760 | 0.90 | CYP3A4 (0.55) | KMT2AWDR5CYP2C9CYP3A4CYP1A2 | |
| SCHEMBL9561274 | 0.86 | CYP3A4 (0.70) | KMT2AWDR5CYP2C9CYP3A4CYP1A2 | |
| SCHEMBL8501299 | 0.86 | CYP2C9 (0.55) | KMT2AWDR5CYP2C9CYP3A4CYP1A2 | |
| SCHEMBL9688514 | 0.86 | CYP3A4 (0.52) | KMT2AWDR5CYP2C9CYP3A4CYP1A2 | |
| SCHEMBL8552373 | 0.85 | CYP2D6 (0.54) | KMT2ACYP2C9CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL8504230 | 0.84 | CYP2C9 (0.53) | KMT2AWDR5CYP2C9CYP3A4CYP1A2 | |
| SCHEMBL8503506 | 0.84 | CYP2C9 (0.60) | KMT2AWDR5CYP2C9CYP3A4CYP1A2 | |
| SCHEMBL8501930 | 0.83 | CYP2C9 (0.53) | KMT2AWDR5CYP2C9CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080070942-A1 | PRAZOLE DERIVATIVES AND SALTS THEREOF AND USE OF SAME | JIANGSU HANSEN PHARMACEUTICAL CO., LTD. (CN) | 2008-03-20 | — | — | US | disclosed |
| CN-100364989-C | Prazole derivative and its salt and use | JIANGSU HAOSEN PHARMACEUTICAL (CN) | 2008-01-30 | — | — | CN | disclosed |
| EP-1795195-A1 | NEW PRAZOLE COMPOUND AND THE USE THEREOF | Jiangsu Hansen Pharmaceutical Co., Ltd. (CN) | 2007-06-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070942-A1 | PRAZOLE DERIVATIVES AND SALTS THEREOF AND USE OF SAME | SLC10A2, GIPR, CACNA1E | KMT2A 2743/4885WDR5 2930/4885CYP2C9 96/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.