SCHEMBL498570

SCHEMBL498570

Cc1ccc(NCC(=O)O)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.54
FFAR1 O14842 1/20 0.54
MAPT P10636 6/20 0.54
POLB P06746 2/20 0.52
KMT2A Q03164 3/20 0.50
CA12 O43570 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
NLRP1 Q9C000 1/20 0.50
CA9 Q16790 1/20 0.50
HTT P42858 1/20 0.48
TDP1 Q9NUW8 2/20 0.48
KDM4E B2RXH2 2/20 0.48
AGTR1 P30556 1/20 0.46
MEN1 O00255 2/20 0.46
LMNA P02545 1/20 0.46
HSP90AA1 P07900 1/20 0.46
HSP90AB1 P08238 1/20 0.46
GAA P10253 1/20 0.46
THRB P10828 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10538782 0.98 ALDH1A1 (0.53) ALDH1A1FFAR1MAPTPOLBKMT2A
Trifluoroacetic Acid SCHEMBL27535061 0.89 FFAR1 (0.50) ALDH1A1FFAR1MAPTPOLBKMT2A
SCHEMBL5692310 0.89 ALDH1A1 (0.44) ALDH1A1FFAR1MAPTPOLBKMT2A
Toluene SCHEMBL28200952 0.88 LMNA (0.47) ALDH1A1FFAR1MAPTKMT2AHTT
SCHEMBL28670574 0.83 LMNA (0.50) ALDH1A1FFAR1MAPTPOLBKMT2A
SCHEMBL9419326 0.83 MAPT (0.54) ALDH1A1FFAR1MAPTPOLBKMT2A
Hydrochloric Acid SCHEMBL10541037 0.82 KMT2A (0.56) ALDH1A1FFAR1MAPTPOLBKMT2A
SCHEMBL808952 0.81 CYP2A6 (0.48) ALDH1A1FFAR1MAPTKMT2ATDP1
Water SCHEMBL11637714 0.81 MAPT (0.52) ALDH1A1FFAR1MAPTPOLBKMT2A
SCHEMBL4572857 0.81 CA12 (0.53) ALDH1A1FFAR1MAPTPOLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 528 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240423878-A2 SELF-ADHESIVE FISSURE SEALANT KULZER GMBH (DE) 2024-12-26 US claimed
US-20240216229-A1 SELF-ADHESIVE FISSURE SEALANT KULZER GMBH (DE) 2024-07-04 US claimed
WO-2024030977-A2 NOVEL MELANOCORTIN ANALOGS SIGHTSTREAM BIOTHERAPEUTICS, INC. (US) 2024-02-08 WO claimed
EP-4312947-A1 SELF-ADHESIVE FISSURE SEALANT Kulzer GmbH (DE) 2024-02-07 EP claimed
CN-117503616-A Self-adhesive resin water heater with self-curing stability and preparation method thereof 日照沪鸽生物材料有限公司 2024-02-06 CN claimed
EP-3027164-B1 FORMULATIONS AND MATERIALS WITH CATIONIC POLYMERS UCL BUSINESS LTD (GB) 2023-06-07 EP claimed
CN-113480485-B 1,2, 4-triaryl-1, 2, 4-triazoles compound and synthetic method thereof 甘肃农业大学 2023-04-07 CN claimed
WO-2022207879-A1 SELF-ADHESIVE FISSURE SEALANT KULZER GMBH (DE) 2022-10-06 WO claimed
US-20150166606-A1 PEPTIDE AND PEPTIDOMIMETIC INHIBITORS RA PHARMACEUTICALS, INC. 2015-06-18 US claimed
EP-2056757-A2 BIOCOMPATIBLE STENT Den-Mat Holdings LLC (US) 2009-05-13 EP claimed
US-RE34937-E Adhesive bonding of acrylic resins, especially in dentistry DEN-MAT CORPORATION (US) 1995-05-16 US claimed
US-5401783-A Adhesion-promoting agents incorporating polyvalent cations AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1995-03-28 US claimed
US-5348988-A Reaction of dianhydride with unsaturated alcohol to form ester groups BISCO, INC. (US) 1994-09-20 US claimed
EP-0377072-B1 Adhesive bonding of acrylic resins, especially in dentistry DEN MAT CORP (US) 1994-02-02 EP claimed
US-5270351-A Adhesion-promoting agents incorporating polyvalent cations AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1993-12-14 US claimed
US-4964911-A Adhesive bonding of acrylic resins, especially in dentistry DEN-MAT CORPORATION (US) 1990-10-23 US claimed
EP-0377072-A1 Adhesive bonding of acrylic resins, especially in dentistry DEN MAT CORPORATION (US) 1990-07-11 EP claimed
US-4659751-A Simplified method for obtained strong adhesive bonding of composites to dentin, enamel and other substrates AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1987-04-21 US claimed
US-4588756-A Multi-step method for obtaining strong adhesive bonding of composites to dentin, enamel and other substrates AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1986-05-13 US claimed
US-4514527-A TREATING WITH AQUEOUS SOLUTION OF CARBOXY-CONTAINING SALT AND HAVING AN OXIDIZABLE CATION AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1985-04-30 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150166606-A1 PEPTIDE AND PEPTIDOMIMETIC INHIBITORS KLKB1, KLK1, KLK5 ALDH1A1 4182/4885FFAR1 3142/4885MAPT 3321/4885
US-20240423878-A2 SELF-ADHESIVE FISSURE SEALANT ESD, GFER, FUS ALDH1A1 318/4885FFAR1 27/4885MAPT 158/4885
US-20240216229-A1 SELF-ADHESIVE FISSURE SEALANT ESD, GFER, FUS ALDH1A1 318/4885FFAR1 27/4885MAPT 158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.