⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL29124171 | 0.97 | LMNA (0.34) | — | |
| SCHEMBL4986702 | 0.97 | LMNA (0.39) | — | |
| Hydrochloric Acid SCHEMBL28556911 | 0.94 | LMNA (0.38) | — | |
| Sulfuric Acid SCHEMBL10736945 | 0.85 | BLM (0.42) | — | |
| SCHEMBL3589175 | 0.75 | CA2 (0.31) | — | |
| SCHEMBL4984203 | 0.75 | FAAH (0.31) | — | |
| SCHEMBL14000819 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL6271047 | 0.71 | F2 (0.42) | — | |
| SCHEMBL2755822 | 0.69 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL1713380 | 0.68 | F2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108795339-B | Adhesive composition and adhesive film | 藤森工业株式会社 | 2022-03-22 | — | — | CN | claimed |
| CN-107868635-B | Adhesive composition and adhesive film | 藤森工业株式会社 | 2022-03-01 | — | — | CN | claimed |
| CN-109852280-B | Adhesive composition and surface protective film | 藤森工业株式会社 | 2021-09-21 | — | — | CN | claimed |
| CN-108795339-B | Adhesive composition and adhesive film | 藤森工业株式会社 | 2022-03-22 | — | — | CN | disclosed |
| CN-108795348-B | Adhesive composition and surface protective film | 藤森工业株式会社 | 2022-03-04 | — | — | CN | disclosed |
| CN-107868635-B | Adhesive composition and adhesive film | 藤森工业株式会社 | 2022-03-01 | — | — | CN | disclosed |
| CN-109852280-B | Adhesive composition and surface protective film | 藤森工业株式会社 | 2021-09-21 | — | — | CN | disclosed |
| CN-108865017-B | Adhesive composition and surface protective film | 藤森工业株式会社 | 2021-08-24 | — | — | CN | disclosed |
| CN-107523246-B | Adhesive composition and antistatic surface protective film | 藤森工业株式会社 | 2021-04-09 | — | — | CN | disclosed |
| CN-108329246-B | Pyrrolidinyl urea and pyrrolidinyl thiourea compounds as TRKA kinase inhibitors | 阵列生物制药公司 | 2021-02-26 | — | — | CN | disclosed |
| US-10323022-B2 | Pyrrolidinyl urea, pyrrolidinyl thiourea and pyrrolidinyl guanidine compounds as TrkA kinase inhibitors | ARRAY BIOPHARMA INC. (US) | 2019-06-18 | — | — | US | disclosed |
| CN-103649076-A | Pyrrolidinyl urea and pyrrolidinyl thiourea compounds as trka kinase inhibitors | ARRAY BIOPHARMA INC | 2014-03-19 | — | — | CN | disclosed |
| WO-2012158413-A2 | PYRROLIDINYL UREA AND PYRROLIDINYL THIOUREA COMPOUNDS AS TRKA KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2012-11-22 | — | — | WO | disclosed |
| US-7351743-B1 | Therapeutic guanidines | WYETH (US) | 2008-04-01 | — | — | US | disclosed |
| US-20070265348-A1 | N-(4-sec-butylphenyl)-N-benzylguanidine; modulate, particularly inhibit, the release of neurotransmitter such as glutamate; neurodegenerative disease: Parkinson's, Huntington's, Alzheimer's diseases, Amyotrophic Lateral Sclerosis, Down's Syndrome, epilepsy, atrophy, HIV | SCION PHARMACEUTICALS, INC, A DELAWARE CORPORATION | 2007-11-15 | — | — | US | disclosed |
| US-6787569-B1 | INHIBITORS OF NEUROTRANSMITTER (E.G., GLUTAMATE) RELEASE FROM ISCHEMIC NEURONAL CELLS; N,N-DISUBSTITUTED GUANIDINES; NEUROLOGICAL CONDITIONS SUCH AS EPILEPSY, NEURODEGENERATIVE CONDITIONS AND/OR NERVE CELL DEATH FROM STROKE OR HEART ATTACK | CAMBRIDGE NEUROSCIENCE, INC. | 2004-09-07 | — | — | US | disclosed |
| US-6288123-B1 | CENTRAL NERVOUS SYSTEM DISORDERS | CAMBRIDGE NEUROSCIENCES, INC. | 2001-09-11 | — | — | US | disclosed |
| CN-1294593-A | Cephalosporines having cyclic aminoguanidine substituents as antibiotics | BIOCHEMIE GMBH (AT) | 2001-05-09 | — | — | CN | disclosed |
| US-6174924-B1 | Therapeutic guanidines | CAMBRIDGE NEUROSCIENCE, INC. | 2001-01-16 | — | — | US | disclosed |
| US-6143791-A | NERVOUS SYSTEM DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 2000-11-07 | — | — | US | disclosed |