Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4976624 | 0.89 | ALDH1A1 (0.55) | ALDH1A1LMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL1454126 | 0.86 | MAPT (0.47) | ALDH1A1LMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL4975574 | 0.85 | MAPT (0.44) | ALDH1A1LMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL4986203 | 0.81 | MEN1 (0.53) | ALDH1A1LMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL1456217 | 0.77 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL2961835 | 0.75 | MAPT (0.52) | ALDH1A1LMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL4976616 | 0.73 | MEN1 (0.53) | ALDH1A1LMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL4976907 | 0.73 | MAPT (0.51) | ALDH1A1LMNAMAPTSMN1; SMN2HTT | |
| SCHEMBL1455459 | 0.73 | MAPT (0.60) | ALDH1A1LMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL1455627 | 0.72 | MAPT (0.59) | ALDH1A1LMNAMAPTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979348-A2 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007076034-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2007-07-05 | — | — | WO | disclosed |