Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.47 |
| ▸ | PDE7B | Q9NP56 | 3/20 | 0.47 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4986213 | 0.89 | ALDH1A1 (0.55) | ALDH1A1LMNABCL2L1POLBMAPT | |
| SCHEMBL1456217 | 0.87 | ALDH1A1 (0.47) | ALDH1A1LMNABCL2L1POLBMAPT | |
| SCHEMBL4976907 | 0.85 | MAPT (0.51) | ALDH1A1LMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL4976616 | 0.81 | MEN1 (0.53) | ALDH1A1LMNABCL2L1POLBMAPT | |
| SCHEMBL1454126 | 0.78 | MAPT (0.47) | ALDH1A1LMNABCL2L1POLBMAPT | |
| SCHEMBL4975574 | 0.73 | MAPT (0.44) | ALDH1A1LMNAPOLBMAPTKMT2A | |
| SCHEMBL4986203 | 0.73 | MEN1 (0.53) | ALDH1A1LMNABCL2L1POLBMAPT | |
| SCHEMBL20474732 | 0.73 | ALDH1A1 (0.46) | ALDH1A1LMNAPOLBMAPTKMT2A | |
| SCHEMBL1923978 | 0.73 | BCL2L1 (0.74) | ALDH1A1LMNABCL2L1POLBMAPT | |
| SCHEMBL1454864 | 0.72 | MAPT (0.46) | ALDH1A1LMNAMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979348-A2 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007076034-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2007-07-05 | — | — | WO | disclosed |