Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 10/20 | 0.50 |
| ▸ | HTR1D | P28221 | 6/20 | 0.50 |
| ▸ | HTR1B | P28222 | 5/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 8/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 8/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 7/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14092053 | 0.89 | HTR1D (0.49) | ADRA1AHTR1DHTR1BADRA1DADRA1B | |
| SCHEMBL2387364 | 0.87 | ADRA1A (0.45) | ADRA1AHTR1DHTR1BADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL3726001 | 0.86 | ADRA1A (0.44) | ADRA1AHTR1DHTR1BADRA1DADRA1B | |
| SCHEMBL2561416 | 0.86 | HTR1D (0.50) | ADRA1AHTR1DHTR1BADRA1DADRA1B | |
| SCHEMBL4992395 | 0.86 | HTR1D (0.50) | ADRA1AHTR1DHTR1BADRA1DADRA1B | |
| SCHEMBL13752307 | 0.86 | HTR1D (0.50) | ADRA1AHTR1DHTR1BADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL3726850 | 0.85 | HTR1D (0.49) | ADRA1AHTR1DHTR1BADRA1DADRA1B | |
| SCHEMBL14092049 | 0.85 | HTR1D (0.49) | ADRA1AHTR1DHTR1BADRA1DADRA1B | |
| SCHEMBL5200810 | 0.84 | TAAR1 (0.51) | ADRA1AHTR1DADRA1DADRA1BADRA2C | |
| SCHEMBL4993251 | 0.84 | HTR1B (0.48) | ADRA1AHTR1DHTR1BADRA1DADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7407980-B2 | Imidazolinylmethyl aralkylsulfonamides | ROCHE PALO ALTO LLC (US) | 2008-08-05 | — | — | US | disclosed |
| US-7407980-B2 | Imidazolinylmethyl aralkylsulfonamides | ROCHE PALO ALTO LLC (US) | 2008-08-05 | — | — | US | disclosed |
| US-7407980-B2 | Imidazolinylmethyl aralkylsulfonamides | ROCHE PALO ALTO LLC (US) | 2008-08-05 | — | — | US | disclosed |