Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 3/20 | 0.55 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | OGA | O60502 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28267334 | 0.91 | CDC7 (0.52) | CDC7DBF4HSP90AA1RECQLHDAC3 | |
| SCHEMBL21199675 | 0.89 | CDC7 (0.51) | CDC7DBF4HSP90AA1HDAC3HDAC4 | |
| SCHEMBL11725742 | 0.88 | CDC7 (0.50) | CDC7DBF4HSP90AA1HDAC3HDAC4 | |
| SCHEMBL21199652 | 0.88 | CDC7 (0.50) | CDC7DBF4HSP90AA1HDAC3HDAC4 | |
| SCHEMBL1912617 | 0.87 | CDC7 (0.57) | CDC7DBF4HDAC3HDAC4HDAC1 | |
| SCHEMBL11679879 | 0.86 | L3MBTL1 (0.47) | CDC7DBF4ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL3843901 | 0.85 | CDC7 (0.56) | CDC7DBF4HDAC3HDAC4HDAC1 | |
| SCHEMBL5887745 | 0.85 | NPSR1 (0.40) | CDC7DBF4RECQLALDH1A1SMN1; SMN2 | |
| SCHEMBL19590880 | 0.85 | CDC7 (0.50) | CDC7DBF4HSP90AA1HDAC3HDAC4 | |
| SCHEMBL5911684 | 0.84 | CDC7 (0.55) | CDC7DBF4HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984360-A2 | COMPOUNDS AND METHODS FOR MODULATING FX-RECEPTORS | Eli Lilly & Company (US) | 2008-10-29 | — | — | EP | disclosed |
| WO-2007092751-A2 | COMPOUNDS AND METHODS FOR MODULATING FX-RECEPTORS | ELI LILLY AND COMPANY (US) | 2007-08-16 | — | — | WO | disclosed |
| US-4046902-A | VASODILATORS | ROUSSEL UCLAF (FR) | 1977-09-06 | — | — | US | disclosed |
| US-4045567-A | 2-Alkyl-5-thiazole-carboxylic acid derivatives in hypolipemiant compositions | ROUSSEL UCLAF (FR) | 1977-08-30 | — | — | US | disclosed |
| US-3966950-A | ALPHA-ADRENOLYTIC ACTIVITY | ROUSSEL-UCLAF (FR) | 1976-06-29 | — | — | US | disclosed |
| US-3957809-A | VASODILATORS | ROUSSEL-UCLAF (FR) | 1976-05-18 | — | — | US | disclosed |