Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13447371 | 0.90 | TSHR (0.41) | NPSR1L3MBTL1HPGDTSHRMAPK1 | |
| SCHEMBL11730112 | 0.86 | NPSR1 (0.41) | NPSR1L3MBTL1HPGDTSHRMAPK1 | |
| SCHEMBL4989265 | 0.85 | CDC7 (0.55) | HPGDMAPK1CDC7DBF4ALDH1A1 | |
| SCHEMBL2075036 | 0.85 | HDAC6 (0.39) | NPSR1L3MBTL1HPGDTSHRMAPK1 | |
| SCHEMBL3647163 | 0.85 | FFAR2 (0.37) | NPSR1L3MBTL1HPGDTSHRMAPK1 | |
| Tizoprolic Acid SCHEMBL2110604 | 0.84 | HCAR2 (0.53) | L3MBTL1TSHRALDH1A1RECQLGAA | |
| Hydrochloric Acid SCHEMBL2405970 | 0.84 | FFAR2 (0.36) | NPSR1L3MBTL1HPGDTSHRMAPK1 | |
| SCHEMBL11709354 | 0.83 | FFAR2 (0.39) | NPSR1L3MBTL1HPGDTSHRMAPK1 | |
| SCHEMBL13412473 | 0.83 | NPSR1 (0.40) | NPSR1L3MBTL1HPGDTSHRMAPK1 | |
| SCHEMBL11678938 | 0.83 | ALDH1A1 (0.49) | NPSR1L3MBTL1HPGDTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008057336-A2 | HETEROCYCLYL-SUBSTITUTED ANTI-HYPERCHOLESTEROLEMIC COMPOUNDS | MERCK & CO., INC. (US) | 2008-05-15 | — | — | WO | disclosed |
| US-7052742-B1 | Five membered-ring compounds and utilization thereof in liquid crystal mixtures | CLARIANT INTERNATIONAL LTD. (CH) | 2006-05-30 | — | — | US | disclosed |
| US-4045567-A | 2-Alkyl-5-thiazole-carboxylic acid derivatives in hypolipemiant compositions | ROUSSEL UCLAF (FR) | 1977-08-30 | — | — | US | disclosed |