Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 7/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7168178 | 0.87 | MAOB (0.56) | RAB9ASMN1; SMN2MEN1NPC1TP53 | |
| SCHEMBL8741867 | 0.84 | MAOB (0.61) | RAB9ASMN1; SMN2MEN1NPC1TP53 | |
| SCHEMBL6692624 | 0.80 | EPHX2 (0.64) | RAB9ALMNAEPHX2NR1H4TRPV1 | |
| SCHEMBL16692457 | 0.78 | MEN1 (0.57) | RAB9ALMNATRPV1NAMPTSMN1; SMN2 | |
| SCHEMBL4989767 | 0.78 | LMNA (0.60) | RAB9ALMNAEPHX2NR1H4MEN1 | |
| SCHEMBL5923531 | 0.77 | LMNA (0.43) | RAB9ALMNAEPHX2NR1H4TRPV1 | |
| SCHEMBL13167593 | 0.76 | TRPV1 (0.71) | RAB9ALMNAEPHX2NR1H4TRPV1 | |
| SCHEMBL6858815 | 0.75 | LMNA (0.56) | RAB9ALMNAEPHX2NR1H4TRPV1 | |
| SCHEMBL5923365 | 0.75 | RAB9A (0.44) | RAB9ALMNAEPHX2NR1H4TRPV1 | |
| SCHEMBL6692620 | 0.75 | EPHX2 (0.49) | RAB9ALMNAEPHX2NR1H4TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080171756-A1 | N-Substituted Glycine Derivatives: Prolyl Hydroxylase Inhibitors | SMITHKLINE BEECHAM CORPORATION | 2008-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080171756-A1 | N-Substituted Glycine Derivatives: Prolyl Hydroxylase Inhibitors | HIF1AN, EGLN2, EGLN3 | RAB9A 4020/4885LMNA 3270/4885EPHX2 1285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.