Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 6/20 | 0.46 |
| ▸ | MMP8 | P22894 | 5/20 | 0.46 |
| ▸ | MMP14 | P50281 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4986101 | 0.85 | KDM4E (0.41) | MMP9MMP8MMP14KDM4EMAPT | |
| SCHEMBL7263731 | 0.85 | MAPT (0.61) | MMP9MMP8MMP14KDM4EMAPT | |
| SCHEMBL27696220 | 0.85 | MAPT (0.61) | MMP9MMP8MMP14KDM4EMAPT | |
| SCHEMBL928853 | 0.83 | KDM4E (0.39) | MMP9MMP8MMP14KDM4EMAPT | |
| SCHEMBL930299 | 0.80 | ACE (0.65) | MMP9MMP8MMP14KDM4EMAPT | |
| SCHEMBL930376 | 0.80 | KDM4E (0.37) | MMP9MMP8MMP14KDM4EMAPT | |
| SCHEMBL929318 | 0.80 | ACE (0.46) | ACE | |
| SCHEMBL930674 | 0.79 | ACE (0.40) | MMP9MMP8MMP14KDM4EMAPT | |
| SCHEMBL4987659 | 0.79 | KDM4E (0.36) | MMP9MMP8MMP14KDM4EMAPT | |
| SCHEMBL928887 | 0.79 | KDM4E (0.53) | MMP9MMP8MMP14KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080138309-A1 | Use Of Aminodithiol As A Reducing Agent For Hair Perming | L'OREAL S.A. (FR) | 2008-06-12 | — | — | US | claimed |
| US-20080138309-A1 | Use Of Aminodithiol As A Reducing Agent For Hair Perming | L'OREAL S.A. (FR) | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080138309-A1 | Use Of Aminodithiol As A Reducing Agent For Hair Perming | AASDHPPT, BHMT2, ALAD | MMP9 2823/4885MMP8 2675/4885MMP14 3636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.