N-Ethylmaleimide

N-Ethylmaleimide

SCHEMBL4989709

CCN1C(=O)C=CC1=O.CN1C(=O)C=CC1=O

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 13/20 0.80
ALDH1A1 P00352 3/20 0.80
LMNA P02545 2/20 0.80
MAPT P10636 2/20 0.80
NPSR1 Q6W5P4 2/20 0.80
BLM P54132 2/20 0.80
GMNN O75496 1/20 0.80
THPO P40225 1/20 0.80
PMP22 Q01453 1/20 0.80
GSK3A P49840 5/20 0.65
GSK3B P49841 5/20 0.65
FAAH O00519 5/20 0.50
PTGS1 P23219 3/20 0.50
PTGS2 P35354 3/20 0.50
HPGD P15428 2/20 0.48
HSP90AA1 P07900 1/20 0.48
TLR9 Q9NR96 1/20 0.48
TP53 P04637 1/20 0.48
PKM P14618 1/20 0.48
XBP1 P17861 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
N-Ethylmaleimide SCHEMBL18209592 0.89 MGLL (1.00) MGLLALDH1A1LMNAMAPTNPSR1
N-Ethylmaleimide SCHEMBL19666 0.89
N-Ethylmaleimide SCHEMBL28905027 0.87 MGLL (0.94) MGLLALDH1A1LMNAMAPTNPSR1
N-Ethylmaleimide SCHEMBL3675197 0.84 MGLL (0.89) MGLLALDH1A1LMNAMAPTNPSR1
N-Ethylmaleimide SCHEMBL28430583 0.82 MGLL (0.84) MGLLALDH1A1LMNAMAPTNPSR1
N-Ethylmaleimide SCHEMBL9487550 0.82 MGLL (0.84) MGLLALDH1A1LMNAMAPTNPSR1
SCHEMBL25436194 0.81 MGLL (1.00) MGLLALDH1A1LMNAMAPTNPSR1
SCHEMBL36966 0.81
N-Ethylmaleimide SCHEMBL28526355 0.80 MGLL (0.80) MGLLALDH1A1LMNAMAPTNPSR1
N-Ethylmaleimide SCHEMBL8835469 0.78 MGLL (0.76) MGLLALDH1A1LMNAMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109494401-B Holographic polymer electrolyte and preparation method and application thereof 华中科技大学 2021-02-09 CN claimed
CN-109494401-B Holographic polymer electrolyte and preparation method and application thereof 华中科技大学 2021-02-09 CN disclosed
US-20190283128-A1 SILVER NANOWIRES AND METHOD FOR PRODUCING SAME, AND SILVER NANOWIRE INK AND TRANSPARENT CONDUCTIVE FILM DOWA ELECTRONICS MATERIALS CO., LTD. (JP) 2019-09-19 US disclosed
US-20080166091-A1 Polymer Composition, Plastic Optical Fiber, Plastic Optical Fiber Cable, and Method for Manufacturing Plastic Optical Fiber MITSUBISHI RAYON CO., LTD. (JP) 2008-07-10 US disclosed