N-Ethylmaleimide

N-Ethylmaleimide

SCHEMBL28526355

CCN1C(=O)C=CC1=O.N=C=N

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 12/20 0.80
ALDH1A1 P00352 3/20 0.80
LMNA P02545 2/20 0.80
MAPT P10636 2/20 0.80
NPSR1 Q6W5P4 2/20 0.80
BLM P54132 2/20 0.80
GMNN O75496 1/20 0.80
THPO P40225 1/20 0.80
PMP22 Q01453 1/20 0.80
FAAH O00519 5/20 0.45
PTGS1 P23219 4/20 0.45
PTGS2 P35354 4/20 0.45
F2 P00734 1/20 0.43
ELANE P08246 1/20 0.43
CTSG P08311 1/20 0.43
CTRC Q99895 1/20 0.43
HPGD P15428 2/20 0.42
HSP90AA1 P07900 1/20 0.42
TLR9 Q9NR96 1/20 0.42
TP53 P04637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
N-Ethylmaleimide SCHEMBL19666 0.89
N-Ethylmaleimide SCHEMBL18209592 0.89 MGLL (1.00) MGLLALDH1A1LMNAMAPTNPSR1
N-Ethylmaleimide SCHEMBL28905027 0.87 MGLL (0.94) MGLLALDH1A1LMNAMAPTNPSR1
N-Ethylmaleimide SCHEMBL3675197 0.84 MGLL (0.89) MGLLALDH1A1LMNAMAPTNPSR1
N-Ethylmaleimide SCHEMBL8835469 0.83 MGLL (0.76) MGLLALDH1A1LMNAMAPTNPSR1
N-Ethylmaleimide SCHEMBL28430583 0.82 MGLL (0.84) MGLLALDH1A1LMNAMAPTNPSR1
N-Ethylmaleimide SCHEMBL9487550 0.82 MGLL (0.84) MGLLALDH1A1LMNAMAPTNPSR1
N-Ethylmaleimide SCHEMBL4989709 0.80 MGLL (0.80) MGLLALDH1A1LMNAMAPTNPSR1
N-Ethylmaleimide SCHEMBL4636622 0.78 MGLL (0.76) MGLLALDH1A1LMNAMAPTNPSR1
N-Ethylmaleimide SCHEMBL181451 0.78 MGLL (0.76) MGLLALDH1A1LMNAMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112394115-A Method for detecting decoration degree of polyethylene glycol (PEG) repairman of PEGylated recombinant granulocyte stimulating factor 鲁南制药集团股份有限公司 2021-02-23 CN disclosed