N-Ethylmaleimide

N-Ethylmaleimide

SCHEMBL9487550

CCN1C(=O)C=CC1=O.CNC

nearest known ligand 0.84

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 12/20 0.84
ALDH1A1 P00352 3/20 0.84
LMNA P02545 2/20 0.84
MAPT P10636 2/20 0.84
NPSR1 Q6W5P4 2/20 0.84
BLM P54132 2/20 0.84
GMNN O75496 1/20 0.84
THPO P40225 1/20 0.84
PMP22 Q01453 1/20 0.84
FAAH O00519 5/20 0.46
PTGS1 P23219 4/20 0.46
PTGS2 P35354 4/20 0.46
F2 P00734 1/20 0.46
ELANE P08246 1/20 0.46
CTSG P08311 1/20 0.46
CTRC Q99895 1/20 0.46
HPGD P15428 2/20 0.44
HSP90AA1 P07900 1/20 0.44
TLR9 Q9NR96 1/20 0.44
TP53 P04637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
N-Ethylmaleimide SCHEMBL18209592 0.92 MGLL (1.00) MGLLALDH1A1LMNAMAPTNPSR1
N-Ethylmaleimide SCHEMBL19666 0.92
N-Ethylmaleimide SCHEMBL28905027 0.89 MGLL (0.94) MGLLALDH1A1LMNAMAPTNPSR1
N-Ethylmaleimide SCHEMBL3675197 0.86 MGLL (0.89) MGLLALDH1A1LMNAMAPTNPSR1
N-Ethylmaleimide SCHEMBL181451 0.85 MGLL (0.76) MGLLALDH1A1LMNAMAPTNPSR1
N-Ethylmaleimide SCHEMBL28430583 0.84 MGLL (0.84) MGLLALDH1A1LMNAMAPTNPSR1
N-Ethylmaleimide SCHEMBL4989709 0.82 MGLL (0.80) MGLLALDH1A1LMNAMAPTNPSR1
N-Ethylmaleimide SCHEMBL28526355 0.82 MGLL (0.80) MGLLALDH1A1LMNAMAPTNPSR1
Dimethylamine SCHEMBL181615 0.80 MGLL (0.59) MGLLALDH1A1LMNAMAPTNPSR1
N-Ethylmaleimide SCHEMBL8835469 0.80 MGLL (0.76) MGLLALDH1A1LMNAMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-1304112-A None JP disclosed
EP-0263499-B1 PROCESS FOR PRODUCING GRAFTED ALKYD RESIN DAINIPPON INK AND CHEMICALS, INC. (JP) 1993-01-07 EP disclosed
US-5047467-A GRAFT POLYMERIZING WITH A VINYL MONOMER CONTAINING NITROGEN PHOSPHOROUS OR OTHER GROUPS DAINIPPON INK AND CHEMICALS, INC. (JP) 1991-09-10 US disclosed
US-5019623-A Vinyl Monomers Containing Nitrogen or Phosphorus Groups DAINIPPON INK AND CHEMICALS, INC. (JP) 1991-05-28 US disclosed
JP-H01304112-A LATENT CURING AGENT FOR EPOXY RESIN DENKI KAGAKU KOGYO KK 1989-12-07 JP disclosed