SCHEMBL4990159

SCHEMBL4990159

O=S(=O)([O-])C(F)(F)C(F)(F)C(F)(F)C(F)(F)F.c1cc2cc([S+]3CCCC3)ccc2cc1OC1CCCCC1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 6/20 0.35
ABL1 P00519 2/20 0.34
PDK2 Q15119 2/20 0.33
MAOB P27338 3/20 0.33
MTNR1A P48039 1/20 0.32
GRM2 Q14416 1/20 0.30
PTGS2 P35354 1/20 0.30
MAOA P21397 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4991056 0.99 PTGS1 (0.34) PTGS1ABL1PDK2MAOBMTNR1A
SCHEMBL5002069 0.85 PTGS2 (0.38) PTGS1PDK2MAOBPTGS2MAOA
SCHEMBL4997132 0.84 PTGS2 (0.37) PTGS1PDK2MAOBPTGS2MAOA
SCHEMBL5002053 0.84 MEN1 (0.41) PTGS2
SCHEMBL4999098 0.84
SCHEMBL4995775 0.83 LMNA (0.33) ABL1
SCHEMBL4986616 0.83 SCN9A (0.30)
SCHEMBL5002199 0.82
SCHEMBL4997138 0.82 LMNA (0.32) ABL1
SCHEMBL5002233 0.82 MAOA (0.33) MAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7371503-B2 Sulfonium salt compound, photoacid generator, and positive-tone radiation-sensitive resin composition JSR CORPORATION (JP) 2008-05-13 US disclosed
US-20060141383-A1 Sulfonium salts, radiation- sensitive acid generators, and positive radiator-sensitive resin compositions JSR CORPORATION (JP) 2006-06-29 US disclosed
EP-1586570-A1 SULFONIUM SALTS, RADIATION-SENSITIVE ACID GENERATORS, AND POSITIVE RADIATION-SENSITIVE RESIN COMPOSITIONS JSR Corporation (JP) 2005-10-19 EP disclosed