Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 10/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | PPARD | Q03181 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.39 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4990240 | 0.80 | FFAR1 (0.48) | FFAR1PPARGPPARDPPARALMNA | |
| SCHEMBL4971306 | 0.77 | FFAR1 (0.48) | FFAR1PPARGPPARDPPARALMNA | |
| SCHEMBL4968623 | 0.74 | FFAR1 (0.47) | FFAR1PPARDFFAR4RXRAPTPN11 | |
| SCHEMBL4970090 | 0.72 | FFAR1 (0.49) | FFAR1PPARDFFAR4RXRA | |
| SCHEMBL4970323 | 0.71 | FFAR1 (0.48) | FFAR1PPARGPPARDFFAR4RXRA | |
| SCHEMBL18778780 | 0.71 | L3MBTL1 (0.51) | LMNAL3MBTL1PLA2G4B | |
| SCHEMBL4968734 | 0.71 | FFAR1 (0.47) | FFAR1FFAR4RXRAPTPN11 | |
| SCHEMBL4969469 | 0.70 | RXRA (0.47) | FFAR1FFAR4RXRAPTPN11 | |
| SCHEMBL4967940 | 0.70 | RXRA (0.47) | FFAR1FFAR4RXRAPTPN11 | |
| SCHEMBL4969994 | 0.70 | RXRA (0.47) | FFAR1FFAR4RXRAPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781274-B1 | NOVEL BIAROMATIC COMPOUNDS WHICH ACTIVATE RECEPTORS OF PPAR TYPE AND THEIR USE IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RES & DEV (FR) | 2008-11-05 | — | — | EP | disclosed |