Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOB | P04114 | 3/20 | 0.44 |
| ▸ | MTTP | P55157 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL692958 | 0.87 | APOB (0.60) | APOBMTTPKDM4EMAPT | |
| SCHEMBL4990498 | 0.86 | APOB (0.48) | APOBMTTPPOLBHSD17B10ABCB1 | |
| SCHEMBL4990493 | 0.85 | APOB (0.51) | APOBMTTPPOLBHSD17B10ABCB1 | |
| SCHEMBL691418 | 0.79 | MTTP (0.59) | APOBMTTPKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL8408661 | 0.78 | MTTP (0.59) | APOBMTTPKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL3887925 | 0.78 | MTTP (0.59) | APOBMTTPKDM4EMAPT | |
| SCHEMBL8213429 | 0.78 | APOB (0.55) | APOBMTTPKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL8410108 | 0.78 | MTTP (0.58) | APOBMTTPKDM4EMAPT | |
| SCHEMBL8208061 | 0.78 | MTTP (0.53) | APOBMTTPMEN1TP53ALOX15 | |
| SCHEMBL8200807 | 0.78 | MTTP (0.53) | APOBMTTPKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7393958-B2 | Triamide-substituted heterobicyclic compounds | PFIZER, INC. (US) | 2008-07-01 | — | — | US | disclosed |
| US-20070093525-A1 | Triamide-substituted heterobicyclic compounds | PFIZER INC | 2007-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070093525-A1 | Triamide-substituted heterobicyclic compounds | APOB, MTPN, CTRB1 | APOB 1/4885MTTP 7/4885POLB 922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.