Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | MMP12 | P39900 | 1/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | PAM | P19021 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11546209 | 0.90 | CYP2C19 (0.58) | CYP2C19HTTCYP1A2MMP12MMP13 | |
| SCHEMBL8334278 | 0.88 | MMP12 (0.69) | CYP2C19HTTCYP1A2MMP12MMP13 | |
| SCHEMBL20395222 | 0.86 | CYP2C19 (0.59) | CYP2C19HTTCYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL13865680 | 0.85 | HTT (0.56) | CYP2C19HTTCYP1A2MMP12MMP13 | |
| SCHEMBL1478837 | 0.84 | MEN1 (0.66) | CYP2C19ALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL721637 | 0.84 | CYP2C19 (0.57) | CYP2C19HTTCYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL5840786 | 0.84 | CYP2C19 (0.57) | CYP2C19HTTCYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL10560722 | 0.84 | CYP2C19 (0.56) | CYP2C19HTTCYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL1270437 | 0.83 | HTT (0.62) | CYP2C19HTTCYP1A2MMP12MMP13 | |
| Hydrochloric Acid SCHEMBL5506583 | 0.83 | MEN1 (0.63) | CYP2C19ALDH1A1SMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 355 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3962917-A1 | METHOD FOR THE MANUFACTURE OF ALKOXYSILYL-CONTAINING THIOCARBOXYLIC ACID ESTERS | Momentive Performance Materials Inc. (US) | 2022-03-09 | — | — | EP | claimed |
| US-10919920-B2 | Method for the manufacture of alkoxysilyl-containing thiocarboxylic acid esters | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2021-02-16 | — | — | US | claimed |
| WO-2020223068-A1 | METHOD FOR THE MANUFACTURE OF ALKOXYSILYL-CONTAINING THIOCARBOXYLIC ACID ESTERS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2020-11-05 | — | — | WO | claimed |
| US-20200347084-A1 | METHOD FOR THE MANUFACTURE OF ALKOXYSILYL-CONTAINING THIOCARBOXYLIC ACID ESTERS | MOMENTIVE PERFORMANCE MATERIALS INC. | 2020-11-05 | — | — | US | claimed |
| CN-111170983-A | Benzylthio acetamide compound and preparation method and application thereof | 中国农业大学 | 2020-05-19 | — | — | CN | claimed |
| EP-1305015-B1 | SUBSTITUTED STYRYL BENZYLSULFONES FOR TREATING PROLIFERATIVE DISORDERS | UNIV TEMPLE (US) | 2013-06-12 | — | — | EP | claimed |
| JP-4677162-B2 | — | — | 2011-04-27 | — | — | JP | claimed |
| US-20100152491-A1 | PROCESSES FOR PREPARING (E)-STYRYLBENZYLSULFONE COMPOUNDS AND USES THEREOF FOR TREATING PROLIFERATIVE DISORDERS | EPR PHARMACEUTICALS PVT.LTD | 2010-06-17 | — | — | US | claimed |
| US-7732625-B2 | Colorant compounds | XEROX CORPORATION (US) | 2010-06-08 | — | — | US | claimed |
| US-7311767-B2 | Forming a salt of a liquid phase change ink carrier of stearyl stearamide, an amine substituted Xanthene, acridine, anthracene or thioxanthene chromogen, and a metal salt capable of forming a compound with two chromogens | XEROX CORPORATION (US) | 2007-12-25 | — | — | US | claimed |
| US-20050090690-A1 | Process for preparing tetra-amide compounds | XEROX CORPORATION | 2005-04-28 | — | — | US | claimed |
| JP-2003530433-A | — | — | 2003-10-14 | — | — | JP | claimed |
| EP-1305015-A4 | SUBSTITUTED STYRYL BENZYLSULFONES FOR TREATING PROLIFERATIVE DISORDERS | UNIV TEMPLE (US) | 2003-05-21 | — | — | EP | claimed |
| EP-1305015-A1 | SUBSTITUTED STYRYL BENZYLSULFONES FOR TREATING PROLIFERATIVE DISORDERS | Temple University of the Commonwealth System of Higher Education (US) | 2003-05-02 | — | — | EP | claimed |
| US-6486210-B2 | SUCH AS ENANTIOMORPHS OF 4-FLUOROSTYRYL-2,3,4,5,6-PENTAFLUOROBENZYLSULFONE; ANTIPROLIFERATIVE/ANTICANCER AGENTS | Temple University—Of the Commonwealth System of Higher Education | 2002-11-26 | — | — | US | claimed |
| US-20020115643-A1 | Substituted styryl benzylsulfones for treating proliferative disorders | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2002-08-22 | — | — | US | claimed |
| WO-2001078712-A1 | SUBSTITUTED STYRYL BENZYLSULFONES FOR TREATING PROLIFERATIVE DISORDERS | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2001-10-25 | — | — | WO | claimed |
| EP-0494131-A1 | Rubber compositions providing improved rubber-vulcanisate properties | MONSANTO EUROPE S.A./N.V. (BE) | 1992-07-08 | — | — | EP | claimed |
| EP-0158545-B1 | [Alpha-(alkylaminomethyl)-benzylthio]-acetic-acid derivatives, process for their preparation and their therapeutic use | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1987-04-22 | — | — | EP | claimed |
| US-4177114-A | PREPLATING, THIOCYANATE IONS | HITACHI, LTD. (JP) | 1979-12-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152491-A1 | PROCESSES FOR PREPARING (E)-STYRYLBENZYLSULFONE COMPOUNDS AND USES THEREOF FOR TREATING PROLIFERATIVE DISORDERS | PCNA, CDC25B, CCNB1 | CYP2C19 2225/4885HTT 3878/4885CYP1A2 2605/4885 |
| US-20020115643-A1 | Substituted styryl benzylsulfones for treating proliferative disorders | HCCS, CCNO, HRAS | CYP2C19 4680/4885HTT 3547/4885CYP1A2 4786/4885 |
| US-10919920-B2 | Method for the manufacture of alkoxysilyl-containing thiocarboxylic acid esters | TST, MPST, APEH | CYP2C19 2094/4885HTT 1300/4885CYP1A2 3615/4885 |
| US-20050090690-A1 | Process for preparing tetra-amide compounds | TAF9, TAF5, TAF1 | CYP2C19 1364/4885HTT 581/4885CYP1A2 968/4885 |
| US-20200347084-A1 | METHOD FOR THE MANUFACTURE OF ALKOXYSILYL-CONTAINING THIOCARBOXYLIC ACID ESTERS | TST, MPST, APEH | CYP2C19 2094/4885HTT 1300/4885CYP1A2 3615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.