Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.65 |
| ▸ | PPARG | P37231 | 6/20 | 0.63 |
| ▸ | CTSS | P25774 | 3/20 | 0.53 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.45 |
| ▸ | KLK7 | P49862 | 2/20 | 0.45 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | CDC25B | P30305 | 4/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.43 |
| ▸ | CDC25A | P30304 | 2/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4991917 | 1.00 | PPARA (0.65) | PPARAPPARGCTSSCTSKACE | |
| SCHEMBL4997399 | 0.88 | PPARA (0.70) | PPARAPPARGCTSSCTSKACE | |
| SCHEMBL4997387 | 0.88 | PPARA (0.70) | PPARAPPARGCTSSCTSKACE | |
| SCHEMBL1374891 | 0.88 | PPARA (0.76) | PPARAPPARGCTSSCTSKACE | |
| SCHEMBL5001071 | 0.88 | PPARA (0.76) | PPARAPPARGCTSSCTSKACE | |
| SCHEMBL1374896 | 0.88 | PPARA (0.76) | PPARAPPARGCTSSCTSKACE | |
| SCHEMBL21837634 | 0.87 | PPARA (0.59) | PPARAPPARGCTSSCTSKACE | |
| SCHEMBL21837632 | 0.87 | PPARA (0.59) | PPARAPPARGCTSSCTSKACE | |
| SCHEMBL12130757 | 0.85 | PPARA (0.85) | PPARAPPARGCTSSCTSKACE | |
| SCHEMBL4024742 | 0.85 | PPARA (0.63) | PPARAPPARGCTSSACEKLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7396846-B2 | Growth hormone secretagogues | ELI LILLY AND COMPANY (US) | 2008-07-08 | — | — | US | disclosed |
| EP-1497317-B1 | DIPEPTIDIC GROWTH HORMONE SECRETAGOGUES | LILLY CO ELI (US) | 2006-09-06 | — | — | EP | disclosed |
| US-20060167268-A1 | Growth hormone secretagogues | ELI LILLY AND COMPANY, PATENT DIVISION, (US) | 2006-07-27 | — | — | US | disclosed |
| EP-1497316-B1 | GROWTH HORMONE SECRETAGOGUES | LILLY CO ELI (US) | 2006-07-05 | — | — | EP | disclosed |
| US-20050240001-A1 | 2-(2-Amino-2-methylpropionylamino)-3-(2,6-difluoro-3-methylphenyl)methoxy propionic acid N-[5-(4-chlorophenyl)-3,3-dimethyl-1,1-dioxo-2,3-dihydroisothiazol-4-ylmethyl]-N-ethylamide; endogenous human growth hormone controller; non-peptidyl in nature, more metabolically stable | ELI LILLY AND COMPANY (US) | 2005-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167268-A1 | Growth hormone secretagogues | GHSR, GHRHR, CRH | PPARA 1477/4885PPARG 385/4885CTSS 683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.