SCHEMBL4995

SCHEMBL4995

OB(O)c1cccc(C(F)(F)F)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 3/20 1.00
ENPP2 Q13822 6/20 0.50
HTR3E A5X5Y0 1/20 0.48
HTR3B O95264 1/20 0.48
HTR3A P46098 1/20 0.48
HTR3D Q70Z44 1/20 0.48
HTR3C Q8WXA8 1/20 0.48
TRPV6 Q9H1D0 2/20 0.48
CES2 O00748 1/20 0.48
ALDH1A1 P00352 3/20 0.48
TSHR P16473 2/20 0.48
MAPK1 P28482 1/20 0.48
KDM4E B2RXH2 1/20 0.48
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
MMP1 P03956 1/20 0.46
MMP2 P08253 1/20 0.46
MMP9 P14780 1/20 0.46
MMP8 P22894 1/20 0.46
MMP13 P45452 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1668313 0.92 MGLL (0.85) MGLLENPP2HTR3EHTR3BHTR3A
SCHEMBL22718150 0.84 MGLL (0.71) MGLLENPP2ALDH1A1KDM4ECA1
SCHEMBL29438839 0.84 MGLL (0.71) MGLLENPP2ALDH1A1KDM4ECA1
SCHEMBL2030291 0.83 MGLL (0.71) MGLLENPP2TRPV6ALDH1A1KDM4E
SCHEMBL851418 0.83 MGLL (0.71) MGLLENPP2TRPV6ALDH1A1KDM4E
SCHEMBL13660796 0.83 MGLL (0.71) MGLLENPP2TRPV6ALDH1A1KDM4E
SCHEMBL1469967 0.82 MGLL (0.69) MGLLHTR3EHTR3BHTR3AHTR3D
Boric Acid SCHEMBL6255783 0.81 MGLL (0.68) MGLLHTR3EHTR3BHTR3AHTR3D
SCHEMBL3952242 0.80 MGLL (0.67) MGLLENPP2TRPV6ALDH1A1KDM4E
SCHEMBL27909142 0.80 MGLL (0.67) MGLLHTR3EHTR3BHTR3AHTR3D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4108 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250194617-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-06-19 US claimed
CN-116283740-B Synthesis method of drug intermediate 上海添泽生物医药有限公司 2025-06-10 CN claimed
US-20250169514-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-05-29 US claimed
CN-119708726-A Flame-retardant fireproof plate material and preparation method thereof 中坚特信新能源科技(苏州)有限公司 2025-03-28 CN claimed
CN-119118915-A Preparation method of stable isotope labeled fluroxypyr internal standard reagent 谱同生物医药科技(常州)有限公司 2024-12-13 CN claimed
CN-119019883-A Electrolyte membrane additive, electrolyte membrane and application thereof 国家电投集团科学技术研究院有限公司 2024-11-26 CN claimed
CN-118772438-B MOF material based on trifluoromethyl tricarboxylic acid, preparation method and SO2Separation application 德州学院 2024-11-22 CN claimed
CN-118772438-A MOF material based on trifluoromethyl tricarboxylic acid, preparation method and SO2Separation application 德州学院 2024-10-15 CN claimed
CN-118336009-A Phenylboronic acid-based additive and electrolyte for lithium/carbon fluoride primary battery 上海大学 2024-07-12 CN claimed
US-20230380457-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2023-11-30 US claimed
WO-2008039827-A2 POLYMER SYSTEMS FOR LUNG VOLUME REDUCTION THERAPY AERIS THERAPEUTICS, INC. (US) 2008-04-03 WO claimed
US-20070161654-A1 Aryl-isoxazol-4-yl-imidazole derivatives HOFFMANN-LA ROCHE INC. 2007-07-12 US claimed
US-7037905-B2 Pharmaceutical use of boronic acids and esters thereof NOVO NORDISK A/S (DK) 2006-05-02 US claimed
EP-1569925-A1 2-SUBSTITUTED QUINAZOLIN-4-YLAMINE ANALOGUES AS CAPSAICIN RECEPTOR MODULATORS NEUROGEN CORPORATION (US) 2005-09-07 EP claimed
US-6800784-B1 REACTING AROMATIC COMPOUND CARRYING AT LEAST ONE AMINO GROUP AND LEAVING GROUP WITH ARYLBORONIC ACID OR DERIVATIVE THEREOF, IN AQUEOUS MEDIUM, AND IN PRESENCE OF EFFECTIVE QUANTITY OF PALLADIUM CATALYST RHODIA CHIMIE (FR) 2004-10-05 US claimed
WO-2004055003-A1 2-SUBSTITUTED QUINAZOLIN-4-YLAMINE ANALOGUES AS CAPSAICIN RECEPTOR MODULATORS NEUROGEN CORPORATION (US) 2004-07-01 WO claimed
US-20040053889-A1 Pharmaceutical use of boronic acids and esters thereof NOVO NORDISK A/S (DK) 2004-03-18 US claimed
WO-2003105860-A1 PHARMACEUTICAL USE OF BORONIC ACIDS AND ESTERS THEREOF NOVO NORDISK A/S (DK) 2003-12-24 WO claimed
US-6590100-B2 Reacting an aromatic compound bearing a leaving group and an arylboronic acid and/or its derivatives in the presence of a base and an effective amount of a nickel catalyst RHODIA CHIMIE (FR) 2003-07-08 US claimed
US-20020173652-A1 Process for preparing a polyaromatic compound SHASUN PHARMA SOLUTIONS, INC. 2002-11-21 US claimed