Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.67 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.39 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27932331 | 0.84 | MGLL (0.65) | MGLLHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL14703844 | 0.84 | MGLL (0.65) | MGLLHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL4995 | 0.80 | MGLL (1.00) | MGLLHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL23858271 | 0.80 | MGLL (0.59) | MGLLHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7784985 | 0.77 | MGLL (0.56) | MGLLHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL27958386 | 0.76 | TRPV6 (0.61) | MGLLHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL1668314 | 0.76 | MGLL (0.58) | MGLLHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL1469967 | 0.76 | MGLL (0.69) | MGLLHTR3EHTR3BHTR3AHTR3D | |
| Boric Acid SCHEMBL6255783 | 0.75 | MGLL (0.68) | MGLLHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL27879860 | 0.75 | ENPP2 (0.59) | MGLLTSHRCA1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110461848-A | COMPOUNDS AND THEIR USE IN THE TREATMENT OF SCHISTOSOMIASIS | MERCK PATENT GMBH | 2019-11-15 | — | — | CN | disclosed |
| CN-103958475-B | Heteroaryl hydroxamic acid derivatives and their use in the treatment, alleviation or prevention of viral diseases | F. HOFFMANN-LA ROCHE AG (CH) | 2015-11-25 | — | — | CN | disclosed |
| CN-104761521-A | Biphenyl-Substituted Spirocyclic Ketoenols | BAYER CROPSCIENCE AG | 2015-07-08 | — | — | CN | disclosed |
| CN-102056907-B | Heterocyclic derivative and use thereof | TAKEDA PHARMACEUTICAL | 2014-12-31 | — | — | CN | disclosed |
| CN-102137851-B | Compound as vanilloid receptor antagonist, isomer thereof or pharmaceutically acceptable salt thereof, and pharmaceutical composition comprising same | AMOREPACIFIC CORP | 2014-08-27 | — | — | CN | disclosed |
| CN-103958521-A | Pyrimidin-4-one derivatives and their use in the treatment, alleviation or prevention of viral diseases | HOFFMANN LA ROCHE | 2014-07-30 | — | — | CN | disclosed |
| CN-103958475-A | Heteroaryl hydroxamic acid derivatives and their use in the treatment, alleviation or prevention of viral diseases | HOFFMANN LA ROCHE | 2014-07-30 | — | — | CN | disclosed |
| CN-103804422-A | Blue organic electroluminescent phosphorescent material-iridium metal complex, preparation method thereof and organic electroluminescence device | ZHOU MINGJIE | 2014-05-21 | — | — | CN | disclosed |
| CN-103804424-A | Blue organic electroluminescent phosphorescent material-iridium metal complex, preparation method thereof and organic electroluminescence device | ZHOU MINGJIE | 2014-05-21 | — | — | CN | disclosed |
| CN-103804423-A | Blue organic electroluminescent phosphorescent material-iridium metal complex, preparation method thereof and organic electroluminescence device | ZHOU MINGJIE | 2014-05-21 | — | — | CN | disclosed |
| CN-103804421-A | Blue organic electroluminescent phosphorescent material-iridium metal complex, preparation method thereof and organic electroluminescence device | ZHOU MINGJIE | 2014-05-21 | — | — | CN | disclosed |
| CN-101687758-B | Substituted biphenyl carboxylic acids and derivatives thereof | ORTHO MCNEIL PHARM INC | 2014-05-14 | — | — | CN | disclosed |
| CN-102408326-B | Biphenyl-substituted spirocyclic ketoenols | BAYER CROPSCIENCE AG | 2014-04-16 | — | — | CN | disclosed |
| CN-101874021-B | Azaindenofluorenedione derivative, material for organic electroluminescent element, and organic electroluminescent element | IDEMITSU KOSAN CO | 2013-06-19 | — | — | CN | disclosed |