SCHEMBL499513

SCHEMBL499513

CC(=S)c1ccc(C)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.50
CES2 O00748 3/20 0.50
CES1 P23141 3/20 0.50
LMNA P02545 2/20 0.50
SMN1; SMN2 Q16637 3/20 0.48
TDP1 Q9NUW8 5/20 0.47
ACHE P22303 2/20 0.47
PKM P14618 2/20 0.44
HTT P42858 2/20 0.44
ATM Q13315 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
HPGD P15428 1/20 0.44
NLRP1 Q9C000 1/20 0.44
GAA P10253 1/20 0.44
NTSR1 P30989 1/20 0.44
MAPT P10636 2/20 0.44
NPC1 O15118 1/20 0.43
MAPK1 P28482 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20344811 0.80 MAPT (0.32) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL4460667 0.79 ALDH1A1 (0.52) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL1411939 0.77 ALDH1A1 (0.55) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL28879795 0.77 ESR1 (0.52) ALDH1A1LMNASMN1; SMN2ACHEPKM
SCHEMBL5179861 0.77 ALDH1A1 (0.50) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL1034270 0.75 ALDH1A1 (0.55) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL11796637 0.75 ALDH1A1 (0.55) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL8716212 0.74 ESR1 (0.33) SMN1; SMN2HTT
SCHEMBL5068709 0.74 TPMT (0.46) GSK3B
SCHEMBL2163496 0.74 ALDH1A1 (0.55) ALDH1A1CES2CES1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 267 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036569-A Method and system for continuously synthesizing 4-methylsulfonyl acetophenone 江西师范大学 2026-05-15 CN claimed
CN-119100958-B Method for preparing 4-methylsulfonyl acetophenone and/or 4-methylsulfonyl acetophenone by adopting TS-1 molecular sieve 江西师范大学 2025-04-29 CN claimed
CN-119100958-A Method for preparing 4-methylsulfonyl acetophenone and/or 4-methylsulfonyl acetophenone by adopting TS-1 molecular sieve 江西师范大学 2024-12-10 CN claimed
CN-119039135-A Carboxyl chalcone derivative and preparation method and application thereof 四川大学 2024-11-29 CN claimed
CN-117903022-A Application of zirconium hydroxide as catalyst in preparing sulfoxide and sulfone by selective catalytic oxidation of thioether 兰州大学 2024-04-19 CN claimed
CN-115925527-B Method for preparing alpha-diaryl methyl substituted ketone compound 湖南理工学院 2024-02-09 CN claimed
CN-117304135-A Synthesis method of 4-substituted-5H-1, 2, 3-dithiazole-5-thione and derivative 衡阳师范学院 2023-12-29 CN claimed
CN-115925527-A Method for preparing alpha-diaryl methyl substituted ketone compound 湖南理工学院 2023-04-07 CN claimed
CN-113651734-B Method for catalytically oxidizing thioether into sulfone 成都理工大学 2023-02-14 CN claimed
CN-113652716-B Process for electrolyzing high-nickel copper anode by adopting periodic reverse current 江西新金叶实业有限公司 2022-07-12 CN claimed
CN-113651734-A Method for catalytically oxidizing thioether into sulfone 成都理工大学 2021-11-16 CN claimed
CN-113652716-A Process for electrolyzing high-nickel copper anode by adopting periodic reverse current 江西新金叶实业有限公司 2021-11-16 CN claimed
CN-108929276-B Method for preparing pyrimidine compounds from methyl ketone compounds and nitrile compounds 湖南大学 2021-08-31 CN claimed
CN-111363321-A Formula of modified polyarylester plastic 泉州市广进源智能设备有限公司 2020-07-03 CN claimed
EP-1349823-B1 PROCESS FOR BASE-PROMOTED CONDENSATION REACTIONS AND BASE REAGENT THEREFOR CHEMTURA CORP (US) 2007-11-21 EP claimed
EP-1349823-A1 PROCESS FOR BASE-PROMOTED CONDENSATION REACTIONS AND BASE REAGENT THEREFOR Crompton Corporation (US) 2003-10-08 EP claimed
WO-2002055466-A1 PROCESS FOR BASE-PROMOTED CONDENSATION REACTIONS AND BASE REAGENT THEREFOR CROMPTON CORPORATION (US) 2002-07-18 WO claimed
US-6410795-B1 FORMING DIKETONES CROMPTON CORPORATION 2002-06-25 US claimed
CN-122036569-A Method and system for continuously synthesizing 4-methylsulfonyl acetophenone 江西师范大学 2026-05-15 CN disclosed
US-3931152-A ANTITUBERCULAR AMERICAN CYANAMID COMPANY (US) 1976-01-06 US disclosed