SCHEMBL5068709

SCHEMBL5068709

CC(=S)c1ccc(I)cc1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TPMT P51580 1/20 0.46
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
GSK3B P49841 1/20 0.39
IDO1 P14902 1/20 0.37
PHGDH O43175 1/20 0.36
SLC22A2 O15244 1/20 0.32
SLC22A1 O15245 1/20 0.32
SLC22A3 O75751 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
APP P05067 3/20 0.32
PTPN2 P17706 1/20 0.31
PTPN1 P18031 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10899035 0.77 TPMT (0.50) TPMTCA1CA2GSK3BSLC22A2
SCHEMBL6346842 0.74 TPMT (0.55) TPMTCA1CA2GSK3BIDO1
SCHEMBL499513 0.74 ALDH1A1 (0.50) GSK3B
SCHEMBL17187843 0.72 TPMT (0.59) TPMTCA1CA2GSK3B
SCHEMBL457196 0.72 TPMT (0.59) TPMTCA1CA2GSK3B
SCHEMBL8308656 0.72 TPMT (0.46) TPMTCA1CA2GSK3BSLC22A2
SCHEMBL20344811 0.72 MAPT (0.32)
SCHEMBL3182088 0.72 ALDH1A1 (0.48) CA1CA2GSK3B
SCHEMBL8716212 0.72 ESR1 (0.33)
SCHEMBL7429589 0.72 HTT (0.50) TPMTCA1CA2GSK3BIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120064645-A SERS probe combination and kit and method for identifying and/or quantifying platelet-adhesive CTC 复旦大学附属中山医院 2025-05-30 CN disclosed
CN-114956933-A Marker containing isotope oxygen atom and preparation method and application thereof 清华大学 2022-08-30 CN disclosed
EP-1319231-A4 PROGRAMMABLE MOLECULAR DEVICE UNIV WM MARSH RICE (US) 2008-11-19 EP disclosed
US-20050233158-A1 Molecular electronic interconnects TOUR JAMES M 2005-10-20 US disclosed
EP-1542869-A4 MOLECULAR SCALE ELECTRONIC DEVICES UNIV YALE (US) 2005-06-22 EP disclosed
EP-1542869-A2 MOLECULAR SCALE ELECTRONIC DEVICES Yale University (US) 2005-06-22 EP disclosed
US-20050101063-A1 Three-terminal field-controlled molecular devices TOUR JAMES M (US) 2005-05-12 US disclosed
CN-1535466-A Programmable molecular device WM����ʲ��˹��ѧ 2004-10-06 CN disclosed
US-6756605-B1 Molecular scale electronic devices YALE UNIVERSITY 2004-06-29 US disclosed
EP-1319231-A1 PROGRAMMABLE MOLECULAR DEVICE Wm. MARSH RICE UNIVERSITY (US) 2003-06-18 EP disclosed
WO-2003032330-A2 MOLECULAR ELECTRONIC INTERCONNECTS TOUR JAMES M (US) 2003-04-17 WO disclosed
US-20030058697-A1 Programmable molecular device NAVY, SECRETARY OF THE, UNITED STATES OF AMERICA OFFICE OF NAVAL RESEARCH 2003-03-27 US disclosed
WO-2001027972-A9 MOLECULAR SCALE ELECTRONIC DEVICES UNIV YALE (US) 2002-11-14 WO disclosed
WO-2002035580-A2 THREE-TERMINAL FIELD-CONTROLLED MOLECULAR DEVICES MOLECULAR ELECTRONICS CORPORATION (US) 2002-05-02 WO disclosed
WO-2002009117-A1 PROGRAMMABLE MOLECULAR DEVICE WM. MARSH RICE UNIVERSITY (US) 2002-01-31 WO disclosed
WO-2001027972-A2 MOLECULAR SCALE ELECTRONIC DEVICES YALE UNIVERSITY (US) 2001-04-19 WO disclosed