Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IARS1 | P41252 | 5/20 | 0.80 |
| ▸ | TARS1 | P26639 | 2/20 | 0.65 |
| ▸ | MARS1 | P56192 | 1/20 | 0.59 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28937745 | 0.86 | IARS1 (1.00) | IARS1TARS1LARS1 | |
| SCHEMBL31533322 | 0.83 | DOT1L (0.71) | MARS1LARS1 | |
| SCHEMBL7102573 | 0.80 | DPP4 (0.69) | — | |
| SCHEMBL20711309 | 0.79 | TRPM2 (0.66) | — | |
| SCHEMBL21067691 | 0.79 | TARS1 (1.00) | IARS1TARS1MARS1LARS1 | |
| SCHEMBL20711315 | 0.79 | TRPM2 (0.77) | — | |
| SCHEMBL4316150 | 0.79 | TARS1 (1.00) | IARS1TARS1MARS1LARS1 | |
| SCHEMBL2292037 | 0.78 | TRPM2 (0.71) | — | |
| SCHEMBL18314801 | 0.78 | HINT1 (0.62) | — | |
| SCHEMBL20711220 | 0.77 | TRPM2 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10877035-B2 | Advanced drug development and manufacturing | ICAGEN, LLC (US) | 2020-12-29 | — | — | US | disclosed |
| US-20150309021-A1 | Advanced Drug Development and Manufacturing | LOS ALAMOS NATIONAL SECURITY, LLC | 2015-10-29 | — | — | US | disclosed |
| EP-2511844-B1 | X-ray microscope | XRPRO SCIENCES INC (US) | 2015-08-12 | — | — | EP | disclosed |
| EP-2511844-A2 | Advanced drug development and manufacturing | Los Alamos National Security, LLC (US) | 2012-10-17 | — | — | EP | disclosed |
| EP-2084519-B1 | X-RAY FLUORESCENCE ANALYSIS METHOD | LOS ALAMOS NAT SECURITY LLC (US) | 2012-08-01 | — | — | EP | disclosed |
| US-20080220441-A1 | Advanced drug development and manufacturing | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2008-09-11 | — | — | US | disclosed |