Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 4/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 2/20 | 0.35 |
| ▸ | USP7 | Q93009 | 1/20 | 0.35 |
| ▸ | MELK | Q14680 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4995211 | 0.85 | MEN1 (0.46) | ALDH1A1MAP4K1SUV39H2KCNH2SMN1; SMN2 | |
| SCHEMBL5000676 | 0.79 | CHEK1 (0.43) | MAP4K1ROCK2MELK | |
| SCHEMBL4997110 | 0.79 | MAP4K1 (0.48) | FYNALDH1A1NPSR1MAP4K1ACVR1 | |
| SCHEMBL5000621 | 0.77 | MAP4K1 (0.43) | ALDH1A1MAP4K1ACVR1TGFBR1KCNH2 | |
| SCHEMBL5000912 | 0.76 | RBP4 (0.47) | ALDH1A1NPSR1SUV39H2POLBLMNA | |
| SCHEMBL4995032 | 0.75 | MAPT (0.52) | ALDH1A1NPSR1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL5000702 | 0.75 | MAPT (0.45) | ALDH1A1NPSR1SUV39H2POLBSMN1; SMN2 | |
| SCHEMBL14091319 | 0.75 | MAPT (0.55) | ALDH1A1KCNH2SMN1; SMN2 | |
| SCHEMBL5000709 | 0.72 | ALDH1A1 (0.50) | FYNALDH1A1SMN1; SMN2 | |
| SCHEMBL27316386 | 0.72 | SMN1; SMN2 (0.51) | FYNALDH1A1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194574-A1 | Pyrazine Derivatives As Effective Compounds Against Infectious Diseases | AXXIMA PHARMACEUTICALS AG (DE) | 2008-08-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194574-A1 | Pyrazine Derivatives As Effective Compounds Against Infectious Diseases | PRNP, PSEN1, PPP5C | FYN 20/4885ALDH1A1 1034/4885RECQL 2752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.