Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 8/20 | 0.47 |
| ▸ | CASP7 | P55210 | 3/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP9 | P55211 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | CASP2 | P42575 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29644955 | 1.00 | CASP3 (0.47) | CASP3CASP7CASP1CASP9EGFR | |
| SCHEMBL6535582 | 0.78 | CASP3 (0.75) | CASP3CASP7CASP1CASP9 | |
| SCHEMBL6536461 | 0.72 | CASP3 (0.65) | CASP3CASP7CASP1CASP9EGFR | |
| SCHEMBL26327735 | 0.71 | PTGS2 (0.41) | CASP3CASP7CASP1CASP9 | |
| SCHEMBL5000801 | 0.70 | TP53 (0.41) | — | |
| SCHEMBL15453585 | 0.70 | CA1 (0.53) | — | |
| SCHEMBL15453587 | 0.70 | CA1 (0.53) | — | |
| SCHEMBL6951357 | 0.69 | GAA (0.60) | CASP3CASP7CASP1CASP9 | |
| SCHEMBL8307257 | 0.69 | CASP3 (0.75) | CASP3CASP7CASP1CASP9 | |
| SCHEMBL18382140 | 0.68 | HPGD (0.50) | CASP3CASP7CASP1CASP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10877035-B2 | Advanced drug development and manufacturing | ICAGEN, LLC (US) | 2020-12-29 | — | — | US | disclosed |
| US-20150309021-A1 | Advanced Drug Development and Manufacturing | LOS ALAMOS NATIONAL SECURITY, LLC | 2015-10-29 | — | — | US | disclosed |
| EP-2511844-B1 | X-ray microscope | XRPRO SCIENCES INC (US) | 2015-08-12 | — | — | EP | disclosed |
| EP-2511844-A2 | Advanced drug development and manufacturing | Los Alamos National Security, LLC (US) | 2012-10-17 | — | — | EP | disclosed |
| EP-2084519-B1 | X-RAY FLUORESCENCE ANALYSIS METHOD | LOS ALAMOS NAT SECURITY LLC (US) | 2012-08-01 | — | — | EP | disclosed |
| US-20080220441-A1 | Advanced drug development and manufacturing | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2008-09-11 | — | — | US | disclosed |