Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MGAT2 | Q10469 | 2/20 | 0.37 |
| ▸ | STK10 | O94804 | 1/20 | 0.36 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.36 |
| ▸ | ROS1 | P08922 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 3/20 | 0.35 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15453587 | 0.89 | CA1 (0.53) | PTGS2PDK2PDK4CA12CA1 | |
| SCHEMBL15453585 | 0.89 | CA1 (0.53) | PTGS2PDK2PDK4CA12CA1 | |
| SCHEMBL17185517 | 0.80 | CA1 (0.50) | PTGS2CA12CA1CA2CA9 | |
| SCHEMBL17185515 | 0.80 | CA1 (0.50) | PTGS2CA12CA1CA2CA9 | |
| SCHEMBL24556302 | 0.78 | PDK2 (0.40) | PTGS2PDK2PDK4MEN1KMT2A | |
| SCHEMBL9094147 | 0.76 | ACVR1 (0.61) | PTGS2CA12CA1CA2CA9 | |
| SCHEMBL14410532 | 0.72 | PDK2 (0.55) | PDK2PDK4MEN1KMT2AACVR1 | |
| SCHEMBL5893648 | 0.72 | CA12 (0.69) | CA12CA1CA2CA9MAOA | |
| SCHEMBL5000802 | 0.71 | CASP3 (0.47) | CASP3CASP1CASP7CASP9 | |
| SCHEMBL29644955 | 0.71 | CASP3 (0.47) | CASP3CASP1CASP7CASP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11766439-B2 | Human papilloma virus as predictor of cancer prognosis | FOUNDATION MEDICINE, INC. (US) | 2023-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11766439-B2 | Human papilloma virus as predictor of cancer prognosis | TP53, TSG101, EBNA1BP2 | PTGS2 2229/4885PDK2 3001/4885PDK4 3914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.