Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5000830 | 0.89 | MEN1 (0.45) | ALDH1A1LMNAMAPTHTR1AHTR7 | |
| SCHEMBL4993619 | 0.89 | DHFR (0.46) | PIM2MAPTMEN1KMT2AGAA | |
| SCHEMBL4994785 | 0.88 | SLC6A2 (0.47) | ABCG2PIM2ALDH1A1LMNAMAPT | |
| SCHEMBL4993281 | 0.86 | MAPT (0.54) | ABCG2PIM2ALDH1A1LMNAMAPT | |
| SCHEMBL5000864 | 0.86 | RAD52 (0.44) | PIM2ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL5003018 | 0.86 | PIM2 (0.43) | PIM2ALDH1A1HTR1AHTR7MEN1 | |
| SCHEMBL5000803 | 0.86 | THRB (0.44) | PIM2ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL4995172 | 0.86 | PIM1 (0.48) | PIM2LMNAMAPTMEN1KMT2A | |
| SCHEMBL5003300 | 0.85 | DRD2 (0.46) | ABCG2PIM2ALDH1A1LMNAMAPT | |
| SCHEMBL4997580 | 0.85 | CHEK1 (0.57) | PIM2HTR1AHTR7GAAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194574-A1 | Pyrazine Derivatives As Effective Compounds Against Infectious Diseases | AXXIMA PHARMACEUTICALS AG (DE) | 2008-08-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194574-A1 | Pyrazine Derivatives As Effective Compounds Against Infectious Diseases | PRNP, PSEN1, PPP5C | ABCG2 1460/4885PIM2 1679/4885ALDH1A1 1034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.