SCHEMBL500091

SCHEMBL500091

CC(CN1CCOCC1)C(=O)O

nearest known ligand 0.96

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.96
LMNA P02545 2/20 0.59
USP2 O75604 1/20 0.52
HSD17B10 Q99714 2/20 0.48
NPC1 O15118 1/20 0.48
ANPEP P15144 1/20 0.46
GLA P06280 1/20 0.46
MAPT P10636 1/20 0.44
HTT P42858 1/20 0.44
RAB9A P51151 1/20 0.44
ATM Q13315 1/20 0.44
HIF1A Q16665 1/20 0.44
KDM4E B2RXH2 3/20 0.44
L3MBTL1 Q9Y468 2/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
ALOX12 P18054 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27899777 0.98 ALDH1A1 (0.93) ALDH1A1LMNAUSP2HSD17B10NPC1
SCHEMBL9512804 0.86 ALDH1A1 (0.72) ALDH1A1LMNAUSP2HSD17B10NPC1
SCHEMBL1174390 0.85
SCHEMBL14276784 0.84 ALDH1A1 (0.70) ALDH1A1LMNAUSP2HSD17B10NPC1
SCHEMBL7979632 0.82 ALDH1A1 (0.68) ALDH1A1LMNAUSP2HSD17B10NPC1
SCHEMBL7979638 0.82 ALDH1A1 (0.68) ALDH1A1LMNAUSP2HSD17B10NPC1
SCHEMBL23886205 0.81 ALDH1A1 (0.66) ALDH1A1LMNAMAPTHTTRAB9A
SCHEMBL500486 0.81 ALDH1A1 (0.66) ALDH1A1LMNAMAPTHTTRAB9A
SCHEMBL23886134 0.81 ALDH1A1 (0.66) ALDH1A1LMNAMAPTHTTRAB9A
SCHEMBL23886340 0.81 ALDH1A1 (0.66) ALDH1A1LMNAMAPTHTTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109790146-B Pharmaceutical compounds 阿尔麦克探索有限公司 2022-08-23 CN disclosed
CN-114524721-A Synthesis process of methacrolein 郑州中科新兴产业技术研究院 2022-05-24 CN disclosed
US-9586951-B2 Morpholine derivative or salt thereof FUJIFILM CORPORATION (JP) 2017-03-07 US disclosed
US-9586951-B2 Morpholine derivative or salt thereof FUJIFILM CORPORATION (JP) 2017-03-07 US disclosed
EP-3042900-A1 NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF Fujifilm Corporation (JP) 2016-07-13 EP disclosed
US-20160168139-A1 NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF FUJIFILM CORPORATION (JP) 2016-06-16 US disclosed
US-20160168139-A1 NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF FUJIFILM CORPORATION (JP) 2016-06-16 US disclosed
WO-2015030057-A1 NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF 富士フイルム株式会社 (JP) 2015-03-05 WO disclosed
WO-2012148550-A1 PRODRUGS OF THERAPEUTIC COMPOUNDS MYREXIS, INC. (US) 2012-11-01 WO disclosed
US-8105760-B2 Patterning process and pattern surface coating composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-01-31 US disclosed
CN-1947066-B Rinse solution for lithography TOKYO OHKA KOGYO CO LTD 2011-04-13 CN disclosed
US-20090053657-A1 PATTERNING PROCESS AND PATTERN SURFACE COATING COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-02-26 US disclosed
CN-101010640-A Developing solution composition for lithography and method for resist pattern formation TOKYO OHKA KOGYO CO LTD (JP) 2007-08-01 CN disclosed
CN-1947066-A Rinse solution for lithography TOKYO OHKA KOGYO CO LTD (JP) 2007-04-11 CN disclosed
US-6506939-B1 Producing N-substituted acrylamides and tertiary amines CIBA SPECIALTY CHEMICALS WATER TREATMENTS LTD. (GB) 2003-01-14 US disclosed
EP-1140797-A1 PRODUCTION OF ACRYLIC MONOMERS Ciba Specialty Chemicals Water Treatments Limited (GB) 2001-10-10 EP disclosed
WO-2000041996-A1 PRODUCTION OF ACRYLIC MONOMERS CIBA SPECIALTY CHEMICALS WATER TREATMENTS LIMITED (GB) 2000-07-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160168139-A1 NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF PRMT7, RBBP7, RER1 ALDH1A1 2519/4885LMNA 2540/4885USP2 4202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.