SCHEMBL5006597

SCHEMBL5006597

C=C(CCCC1CCCCC1)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM5A P29375 3/20 0.44
PHF8 Q9UPP1 3/20 0.44
KDM2A Q9Y2K7 3/20 0.44
KDM4C Q9H3R0 2/20 0.44
KDM4A O75164 1/20 0.44
CYP1A2 P05177 1/20 0.42
HPGD P15428 1/20 0.42
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
SIGMAR1 Q99720 2/20 0.39
EPHX1 P07099 1/20 0.39
P2RX7 Q99572 1/20 0.38
NAAA Q02083 2/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23926395 0.98 KDM5A (0.42) KDM5APHF8KDM2AKDM4CKDM4A
SCHEMBL4448884 0.94 KDM5A (0.50) KDM5APHF8KDM2AKDM4CKDM4A
SCHEMBL7591133 0.93 KDM5A (0.53) KDM5APHF8KDM2AKDM4CKDM4A
SCHEMBL7590760 0.93 KDM5A (0.53) KDM5APHF8KDM2AKDM4CKDM4A
SCHEMBL14245381 0.93 KDM5A (0.53) KDM5APHF8KDM2AKDM4CKDM4A
SCHEMBL14245337 0.93 KDM5A (0.53) KDM5APHF8KDM2AKDM4CKDM4A
SCHEMBL7594925 0.93 KDM5A (0.53) KDM5APHF8KDM2AKDM4CKDM4A
SCHEMBL7594914 0.93 KDM5A (0.53) KDM5APHF8KDM2AKDM4CKDM4A
SCHEMBL1770283 0.88 HPGD (0.48) KDM5APHF8KDM2AKDM4CKDM4A
SCHEMBL464871 0.88 HPGD (0.48) KDM5APHF8KDM2AKDM4CKDM4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12460032-B2 Compositions with high refractive index and Abbe number Johnson & Johnson Surgical Vision, Inc. (US) 2025-11-04 US claimed
US-20240218102-A1 COMPOSITIONS WITH HIGH REFRACTIVE INDEX AND ABBE NUMBER Johnson & Johnson Surgical Vision, Inc. 2024-07-04 US claimed
EP-3962411-A1 HIGH REACTIVE INDEX, HIGH ABBE COMPOSITIONS Johnson & Johnson Surgical Vision, Inc. (US) 2022-03-09 EP claimed
EP-3634508-B1 HIGH REFRACTIVE INDEX, HIGH ABBE NUMBER INTRAOCULAR LENS MATERIALS ALCON INC (CH) 2021-10-27 EP claimed
WO-2020225686-A1 HIGH REACTIVE INDEX, HIGH ABBE COMPOSITIONS Johnson & Johnson Surgical Vision, Inc. (US) 2020-11-12 WO claimed
EP-4720729-A1 SINGLE PIECE INTRAOCULAR LENS WITH INTEGRALLY COUPLED HAPTICS Johnson & Johnson Surgical Vision, Inc. (US) 2026-04-08 EP disclosed
US-20260028439-A1 COMPOSITIONS WITH HIGH REFRACTIVE INDEX AND ABBE NUMBER JOHNSON & JOHNSON SURGICAL VISION INC (US) 2026-01-29 US disclosed
US-12460032-B2 Compositions with high refractive index and Abbe number Johnson & Johnson Surgical Vision, Inc. (US) 2025-11-04 US disclosed
US-20240384021-A1 HIGH REFRACTIVE INDEX, HIGH ABBE COMPOSITIONS JOHNSON & JOHNSON SURGICAL VISION INC (US) 2024-11-21 US disclosed
US-12071497-B2 High refractive index, high Abbe compositions Johnson & Johnson Surgical Vision, Inc. (US) 2024-08-27 US disclosed
US-20240218102-A1 COMPOSITIONS WITH HIGH REFRACTIVE INDEX AND ABBE NUMBER Johnson & Johnson Surgical Vision, Inc. 2024-07-04 US disclosed
US-11958923-B2 Compositions with high refractive index and abbe number Johnson & Johnson Surgical Vision, Inc. (US) 2024-04-16 US disclosed
US-7417090-B2 Water-dispersible polyisocyanate composition, production thereof, and water-based curable composition and application thereof DAINIPPON INK & CHEMICALS, INC. (JP) 2008-08-26 US disclosed
EP-1455739-B1 COSMETIC AGENT CONTAINING AT LEAST ONE COPOLYMER HAVING N-VINYLLACTAM UNITS BASF AG (DE) 2007-11-28 EP disclosed
US-20070049691-A1 Water-dispersible polyisocyanate composition, production thereof, and water-based curable composition and application thereof DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-03-01 US disclosed
EP-0876252-B1 USE OF POLYMERS BASED ON ETHYLENE, (METH)ACRYLIC ACID ESTERS AND (METH)ACRYLIC ACID FOR SEALING PANES OF LAMINATED SAFETY GLASS BASF AG (DE) 2002-10-16 EP disclosed
EP-0580045-A1 Compatible polymer mixtures from copolycarbomates and methycrylate copolymers Röhm GmbH (DE) 1994-01-26 EP disclosed
EP-0580046-A1 UV-absorbing coating layers for copolycarbonates Röhm GmbH (DE) 1994-01-26 EP disclosed
EP-0171755-B1 VINYL-CARBOXYLIC-ACID ESTERS RÖHM GMBH (DE) 1988-05-25 EP disclosed
EP-0171755-A1 Vinyl-carboxylic-acid esters RÖHM GMBH (DE) 1986-02-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260028439-A1 COMPOSITIONS WITH HIGH REFRACTIVE INDEX AND ABBE NUMBER SMCHD1, MACF1, LAGE3 KDM5A 3093/4885PHF8 2531/4885KDM2A 2411/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.