Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 2/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1770283 | 1.00 | HPGD (0.48) | HPGDMEN1KMT2AHSD11B1TP53 | |
| SCHEMBL5003948 | 0.98 | HPGD (0.46) | HPGDMEN1KMT2AHSD11B1TP53 | |
| SCHEMBL1733992 | 0.89 | TET2 (0.35) | HPGDMEN1KMT2ATP53KDM5A | |
| SCHEMBL5006597 | 0.88 | KDM5A (0.44) | HPGDMEN1KMT2AKDM5APHF8 | |
| SCHEMBL4448884 | 0.86 | KDM5A (0.50) | HPGDMEN1KMT2AKDM5APHF8 | |
| SCHEMBL23926395 | 0.86 | KDM5A (0.42) | HPGDMEN1KMT2ATP53KDM5A | |
| SCHEMBL14245337 | 0.85 | KDM5A (0.53) | HPGDMEN1KMT2AKDM5APHF8 | |
| SCHEMBL7594925 | 0.85 | KDM5A (0.53) | HPGDMEN1KMT2AKDM5APHF8 | |
| SCHEMBL7591133 | 0.85 | KDM5A (0.53) | HPGDMEN1KMT2AKDM5APHF8 | |
| SCHEMBL14245381 | 0.85 | KDM5A (0.53) | HPGDMEN1KMT2AKDM5APHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12460032-B2 | Compositions with high refractive index and Abbe number | Johnson & Johnson Surgical Vision, Inc. (US) | 2025-11-04 | — | — | US | claimed |
| US-20240218102-A1 | COMPOSITIONS WITH HIGH REFRACTIVE INDEX AND ABBE NUMBER | Johnson & Johnson Surgical Vision, Inc. | 2024-07-04 | — | — | US | claimed |
| US-11732156-B2 | Method for adhering cured silicones to low energy plastics and composite prepared by the method | DOW SILICONES CORPORATION (US) | 2023-08-22 | — | — | US | claimed |
| EP-3962411-A1 | HIGH REACTIVE INDEX, HIGH ABBE COMPOSITIONS | Johnson & Johnson Surgical Vision, Inc. (US) | 2022-03-09 | — | — | EP | claimed |
| EP-3634508-B1 | HIGH REFRACTIVE INDEX, HIGH ABBE NUMBER INTRAOCULAR LENS MATERIALS | ALCON INC (CH) | 2021-10-27 | — | — | EP | claimed |
| WO-2020225686-A1 | HIGH REACTIVE INDEX, HIGH ABBE COMPOSITIONS | Johnson & Johnson Surgical Vision, Inc. (US) | 2020-11-12 | — | — | WO | claimed |
| EP-3601414-A1 | METHOD FOR ADHERING CURED SILICONES TO LOW ENERGY PLASTICS AND COMPOSITE PREPARED BY THE METHOD | Dow Silicones Corporation (US) | 2020-02-05 | — | — | EP | claimed |
| US-20200032119-A1 | METHOD FOR ADHERING CURED SILICONES TO LOW ENERGY PLASTICS AND COMPOSITE PREPARED BY THE METHOD | DOW SILICONES CORPORATION | 2020-01-30 | — | — | US | claimed |
| WO-2018182950-A1 | METHOD FOR ADHERING CURED SILICONES TO LOW ENERGY PLASTICS AND COMPOSITE PREPARED BY THE METHOD | DOW SILICONES CORPORATION (US) | 2018-10-04 | — | — | WO | claimed |
| US-12624168-B2 | Methods for making polyfunctional organosiloxanes and compositions containing same | DOW SILICONES CORPORATION (US) | 2026-05-12 | — | — | US | disclosed |
| EP-4720729-A1 | SINGLE PIECE INTRAOCULAR LENS WITH INTEGRALLY COUPLED HAPTICS | Johnson & Johnson Surgical Vision, Inc. (US) | 2026-04-08 | — | — | EP | disclosed |
| US-20260028439-A1 | COMPOSITIONS WITH HIGH REFRACTIVE INDEX AND ABBE NUMBER | JOHNSON & JOHNSON SURGICAL VISION INC (US) | 2026-01-29 | — | — | US | disclosed |
| US-12460032-B2 | Compositions with high refractive index and Abbe number | Johnson & Johnson Surgical Vision, Inc. (US) | 2025-11-04 | — | — | US | disclosed |
| EP-3898775-B1 | POLYFUNCTIONAL ORGANOSILOXANES, COMPOSITIONS CONTAINING SAME, AND METHODS FOR THE PREPARATION THEREOF | DOW SILICONES CORP (US) | 2025-03-12 | — | — | EP | disclosed |
| US-20020028894-A1 | Amine organoborane complex polymerization initiators and polymerizable compositions | DOW GLOBAL TECHNOLOGIES INC. | 2002-03-07 | — | — | US | disclosed |
| US-20020025381-A1 | Amine organoborane complex polymerization initiators and polymerizable compositions | DOW GLOBAL TECHNOLOGIES INC. | 2002-02-28 | — | — | US | disclosed |
| WO-2001044311-A1 | AMINE ORGANOBORANE COMPLEX POLYMERIZATION INITIATORS AND POLYMERIZABLE COMPOSITIONS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2001-06-21 | — | — | WO | disclosed |
| US-4587300-A | COMPOSITE RESIN MATRICES | HERCULES INCORPORATED (US) | 1986-05-06 | — | — | US | disclosed |
| EP-0147058-A2 | Low density, polybutadiene based, wet filament winding resin | HERCULES INCORPORATED (US) | 1985-07-03 | — | — | EP | disclosed |
| US-4499240-A | CURABLE BLEND WITH UNSATURATED MONOMER AND FREE RADICAL CATALYSTS | HERCULES INCORPORATED (US) | 1985-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260028439-A1 | COMPOSITIONS WITH HIGH REFRACTIVE INDEX AND ABBE NUMBER | SMCHD1, MACF1, LAGE3 | HPGD 1532/4885MEN1 1293/4885KMT2A 2534/4885 |
| US-11732156-B2 | Method for adhering cured silicones to low energy plastics and composite prepared by the method | DNMT3B, OXER1, MSMO1 | HPGD 892/4885MEN1 594/4885KMT2A 3651/4885 |
| US-20200032119-A1 | METHOD FOR ADHERING CURED SILICONES TO LOW ENERGY PLASTICS AND COMPOSITE PREPARED BY THE METHOD | DNMT3B, OXER1, MSMO1 | HPGD 892/4885MEN1 594/4885KMT2A 3651/4885 |
| US-12624168-B2 | Methods for making polyfunctional organosiloxanes and compositions containing same | HAO2, H1-2, HRH2 | HPGD 2507/4885MEN1 2755/4885KMT2A 1091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.