SCHEMBL50068

SCHEMBL50068

Cc1cc2ccccc2c(O)c1C

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TRPM4 Q8TD43 1/20 0.50
CYP1A2 P05177 3/20 0.48
CYP2A6 P11509 3/20 0.48
ALDH1A1 P00352 3/20 0.47
HSD17B10 Q99714 2/20 0.47
HPGD P15428 1/20 0.47
LMNA P02545 1/20 0.47
HTT P42858 1/20 0.47
PTPN22 Q9Y2R2 1/20 0.45
TSHR P16473 1/20 0.45
HIF1A Q16665 1/20 0.44
CYP1B1 Q16678 1/20 0.44
PKM P14618 1/20 0.44
NQO2 P16083 1/20 0.43
CASP6 P55212 1/20 0.43
PTGS1 P23219 1/20 0.42
PTGS2 P35354 1/20 0.42
NQO1 P15559 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30364741 1.00 TRPM4 (0.50) TRPM4CYP1A2CYP2A6ALDH1A1HSD17B10
SCHEMBL4172887 0.84 LMNA (0.54) TRPM4CYP1A2CYP2A6ALDH1A1HSD17B10
SCHEMBL15485758 0.83 NQO1 (0.50) TRPM4CYP1A2CYP2A6ALDH1A1HSD17B10
SCHEMBL9233004 0.83 TRPM4 (0.61) TRPM4CYP1A2CYP2A6ALDH1A1HSD17B10
SCHEMBL30071634 0.83 LMNA (0.52) TRPM4CYP1A2CYP2A6ALDH1A1HSD17B10
SCHEMBL29771816 0.83 TRPM4 (0.61) TRPM4CYP1A2CYP2A6ALDH1A1HSD17B10
SCHEMBL3953630 0.83 LMNA (0.52) TRPM4CYP1A2CYP2A6ALDH1A1HSD17B10
Hydrochloric Acid SCHEMBL28848790 0.82 CYP1A2 (0.54) TRPM4CYP1A2CYP2A6ALDH1A1HSD17B10
SCHEMBL23110575 0.82 CYP1A2 (0.44) TRPM4CYP1A2CYP2A6ALDH1A1HSD17B10
SCHEMBL15910812 0.82 ALDH1A1 (0.50) CYP1A2CYP2A6ALDH1A1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250011655-A1 RENEWABLE JET PRODUCTION FROM CATALYTIC PYROLYSIS FEEDSTOCK IFP Energies Nouvelles (FR) 2025-01-09 US claimed
EP-4433553-A1 RENEWABLE JET PRODUCTION FROM CATALYTIC PYROLYSIS FEEDSTOCK IFP Energies nouvelles (FR) 2024-09-25 EP claimed
WO-2023088772-A1 RENEWABLE JET PRODUCTION FROM CATALYTIC PYROLYSIS FEEDSTOCK IFP Energies Nouvelles (FR) 2023-05-25 WO claimed
US-10364322-B2 Naphthalene-containing polymers and methods of making the same ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2019-07-30 US claimed
US-20180208716-A1 NAPHTHALENE-CONTAINING POLYMERS AND METHODS OF MAKING THE SAME Alliance for Energy Innovation, LLC 2018-07-26 US claimed
CN-101448771-B Patchouli odorant FIRMENICH & CIE 2012-03-21 CN claimed
EP-1841723-A1 DECALINE DERIVED COMPOUNDS AS PHARMACEUTICALLY ACTIVE AGENTS Universität Dortmund (DE) 2007-10-10 EP claimed
WO-2006069787-A1 DECALINE-DERIVED COMPOUNDS AS PHARMACEUTICALLY ACTIVE AGENTS Universität Dortmund (DE) 2006-07-06 WO claimed
JP-10316625-A None JP disclosed
US-20250282945-A1 CURABLE RESIN COMPOSITION AND ELECTRONIC COMPONENT DEVICE RESONAC CORPORATION (JP) 2025-09-11 US disclosed
CN-120059458-A Resin composition 味之素株式会社 2025-05-30 CN disclosed
CN-119859380-A Resin composition 味之素株式会社 2025-04-22 CN disclosed
CN-119639227-A Resin composition 味之素株式会社 2025-03-18 CN disclosed
CN-119552478-A Resin composition 味之素株式会社 2025-03-04 CN disclosed
US-4097461-A Oxidative coupling of alkylphenols or 1-naphthols catalyzed by metal complexes of diketo compounds ICI AMERICAS INC. (US) 1978-06-27 US disclosed
US-4096190-A Oxidative coupling of alkylphenols catalyzed by metal ammonia complexes ICI AMERICAS INC. (US) 1978-06-20 US disclosed
US-4085124-A Oxidative coupling of alkylphenols, alkoxyphenols and 1-naphthols catalyzed by metal complexes of amino compounds ICI AMERICAS INC. (US) 1978-04-18 US disclosed
US-4070383-A COPPER COMPOUND-ANIONIC SURFACTANT-ALKALI METAL COMPOUND CATALYST SYSTEM ICI AMERICAS INC. (US) 1978-01-24 US disclosed
US-4067890-A Oxidative coupling of alkylphenols, alkoxyphenols and naphthols catalyzed by metal complexes of amino carboxylic and amino sulfonic acids ICI AMERICA INC. (US) 1978-01-10 US disclosed
US-3987068-A COPPER-NITRILE COMPLEX CATALYST E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180208716-A1 NAPHTHALENE-CONTAINING POLYMERS AND METHODS OF MAKING THE SAME NCL, NUCB2, NOC2L TRPM4 4859/4885CYP1A2 556/4885CYP2A6 1823/4885
US-10364322-B2 Naphthalene-containing polymers and methods of making the same NCL, NUCB2, NOC2L TRPM4 4859/4885CYP1A2 556/4885CYP2A6 1823/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.