SCHEMBL5006826

SCHEMBL5006826

CO[Zr]1(OC)C2C(C)=C(c3c(Br)cccc32)[Si](C)(C)C2=C(C)C1c1cccc(Br)c12

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PBRM1 Q86U86 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5003144 0.83 PBRM1 (0.35) PBRM1
SCHEMBL5003588 0.79 PBRM1 (0.33) PBRM1
SCHEMBL5004391 0.78 PBRM1 (0.35) PBRM1
SCHEMBL5352023 0.69 PBRM1 (0.30) PBRM1
SCHEMBL5352525 0.66 GABRA1 (0.32)
SCHEMBL5067415 0.64 PDCD1 (0.31)
SCHEMBL5347817 0.58 PBRM1 (0.33) PBRM1
Hydrochloric Acid SCHEMBL15329541 0.56 PBRM1 (0.30) PBRM1
SCHEMBL23443980 0.55 PBRM1 (0.36) PBRM1
SCHEMBL2970600 0.55 PBRM1 (0.36) PBRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7446216-B2 Halogen substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-11-04 US disclosed
US-20060183874-A1 Halogen substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060183874-A1 Halogen substituted metallocene compounds for olefin polymerization B2M, CDYL, MLX PBRM1 1809/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.