Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6065652 | 0.90 | EDNRB (0.32) | — | |
| SCHEMBL5352543 | 0.88 | — | — | |
| SCHEMBL797335 | 0.87 | PDCD1 (0.30) | PDCD1CD274 | |
| SCHEMBL6065476 | 0.87 | EDNRB (0.36) | — | |
| SCHEMBL7597783 | 0.86 | — | — | |
| SCHEMBL5914834 | 0.85 | BRD4 (0.31) | — | |
| SCHEMBL5359553 | 0.84 | HDAC4 (0.36) | — | |
| SCHEMBL6065058 | 0.84 | EDNRB (0.32) | — | |
| SCHEMBL7878204 | 0.83 | PDCD1 (0.31) | PDCD1CD274 | |
| SCHEMBL5353707 | 0.82 | DHFR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410665-B1 | POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | claimed |
| US-7442667-B2 | Preparation of supported cocatalysts | BOSELL POLYOLEFINE GMBH (DE) | 2008-10-28 | — | — | US | disclosed |
| US-20070149387-A1 | Preparation of supported cocatalysts | BASELL POLYOLEFINE GMBH (DE) | 2007-06-28 | — | — | US | disclosed |
| US-7202190-B1 | Supported catalyst system for the polymerization of olefins | TARGOR GMBH (DE) | 2007-04-10 | — | — | US | disclosed |
| EP-1697432-A2 | PREPARATION OF SUPPORTED COCATALYSTS | Basell Polyolefine GmbH (DE) | 2006-09-06 | — | — | EP | disclosed |
| US-20060154804-A1 | Preparation of dialkyl-ansa-metallocenes | BASELL POLYOLEFINE GMBH (DE) | 2006-07-13 | — | — | US | disclosed |
| US-6953829-B2 | Catalyst system and the use thereof | BASELL POLYOLEFINE GMBH (DE) | 2005-10-11 | — | — | US | disclosed |
| WO-2005063831-A2 | PREPARATION OF SUPPORTED COCATALYSTS | BASELL POLYOLEFINE GMBH (DE) | 2005-07-14 | — | — | WO | disclosed |
| EP-1461346-B1 | PREPARATION OF DIALKYL-ANSA-METALLOCENES | BASELL POLYOLEFINE GMBH (DE) | 2005-04-13 | — | — | EP | disclosed |
| EP-1461346-A1 | PREPARATION OF DIALKYL-ANSA-METALLOCENES | Basell Polyolefine GmbH (DE) | 2004-09-29 | — | — | EP | disclosed |
| US-20010021755-A1 | Metallocenes containing aryl-substituted indenyl derivatives as ligands, process for their preparation, and their use as catalysts | KUBER FRANK (DE) | 2001-09-13 | — | — | US | disclosed |
| US-6271164-B1 | METALLOCENE CATALYST | LYONDELL CHEMICAL TECHNOLOGY, L.P. | 2001-08-07 | — | — | US | disclosed |
| US-6255506-B1 | SUPPORTED SYSTEM IN POLYMERIZATION OR COPOLYMERIZATION OF HIGH MOLECULAR WEIGHT POLYOLEFINS OF HIGH ISOTACTICITY AND NARROW MOLECULAR-WEIGHT DISTRIBUTION; FILMS, SHEETS OR LARGE HOLLOW ARTICLES OR MOLDINGS | TARGOR GMBH (DE) | 2001-07-03 | — | — | US | disclosed |
| US-6242544-B1 | POLYOLEFINS PREPARED USING SOLUBLE METALLOCENE COMPOUNDS IN COMBINATION WITH ALUMINOXANES; HIGH MOLECULAR WEIGHT AND ISOTACTICITY | TARGOR GMBH (DE) | 2001-06-05 | — | — | US | disclosed |
| US-6177526-B1 | METALLOCENE; COCATALYST; MODIFIED OXIDE CONTAINS ORGANIC SILICON RADICALS CONTAINING AT LEAST ONE OF THE GROUPS NITROGEN, FLUORINE, PHOSPHORUS OR SULFUR. | TARGOR GMBH (DE) | 2001-01-23 | — | — | US | disclosed |
| US-6177376-B1 | REACTING METALLOCENE WITH ORGANOLITHIUM COMPOUND AND GRIGNARD COMPOUND, ACTIVATION, CONTACTING WITH SUPPORT | TARGOR GMBH (DE) | 2001-01-23 | — | — | US | disclosed |
| US-6051727-A | A POLYMERIZATION CATALYST FOR POLYOLEFINS OF HIGH MOLECULAR WEIGHT, OF PARTICULAR IMPORTANCE FOR THE PRODUCTION OF FILMS, SHEETS OR LARGE HOLLOW ARTICLES OR MOLDINGS SUCH AS PIPES | TARGOR GMBH (DE) | 2000-04-18 | — | — | US | disclosed |
| US-5840644-A | OLEFIN POLYMERIZATION CATALYSTS | TARGOR GMBH (DE) | 1998-11-24 | — | — | US | disclosed |
| US-5786432-A | POLYMERIZING OR COPOLYMERIZING OLEFIN IN PRESENCE OF TRANSITION METAL METALLOCENE CATALYST AND COCATALYST | TARGOR GMBH (DE) | 1998-07-28 | — | — | US | disclosed |
| US-5770753-A | ADDITION POLYMERIZATION CATALYST | TARGOR GMBH (DE) | 1998-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060154804-A1 | Preparation of dialkyl-ansa-metallocenes | C1R, SOD1, RPSA | PDCD1 2148/4885CD274 558/4885CHRNB2 2334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.