SCHEMBL5007585

SCHEMBL5007585

NC(CN(CC(N)C(=O)c1ccccc1O)CC(N)C(=O)c1ccccc1O)C(=O)c1ccccc1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 7/20 0.47
KDM4E B2RXH2 6/20 0.47
TSHR P16473 4/20 0.47
ALDH1A1 P00352 3/20 0.47
HSD17B10 Q99714 3/20 0.47
MAPT P10636 2/20 0.47
SMN1; SMN2 Q16637 3/20 0.44
CA1 P00915 2/20 0.44
CA9 Q16790 2/20 0.44
CA12 O43570 1/20 0.44
CA2 P00918 1/20 0.44
HMGB1 P09429 1/20 0.44
CA4 P22748 1/20 0.44
CA6 P23280 1/20 0.44
CA7 P43166 1/20 0.44
NAPRT Q6XQN6 1/20 0.44
CA14 Q9ULX7 1/20 0.44
TDP1 Q9NUW8 3/20 0.41
HIF1A Q16665 2/20 0.41
GAA P10253 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11179021 0.81 KDM4E (0.50) HPGDKDM4ETSHRALDH1A1HSD17B10
SCHEMBL8411463 0.80 KDM4E (0.48) HPGDKDM4ETSHRALDH1A1HSD17B10
SCHEMBL10824784 0.80 KDM4E (0.48) HPGDKDM4ETSHRALDH1A1HSD17B10
SCHEMBL8411467 0.80 KDM4E (0.48) HPGDKDM4ETSHRALDH1A1HSD17B10
SCHEMBL29524852 0.79 KDM4E (0.52) HPGDKDM4ETSHRALDH1A1HSD17B10
SCHEMBL30367223 0.79 KDM4E (0.48) HPGDKDM4ETSHRALDH1A1HSD17B10
SCHEMBL726909 0.76 KDM4E (0.46) HPGDKDM4ETSHRALDH1A1HSD17B10
SCHEMBL11575219 0.76 KDM4E (0.48) HPGDKDM4ETSHRALDH1A1HSD17B10
SCHEMBL11575221 0.76 KDM4E (0.48) HPGDKDM4ETSHRALDH1A1HSD17B10
SCHEMBL11349279 0.75 SLC7A5 (0.57) HPGDKDM4ETSHRALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080293155-A1 SALICYLAMIDE-LANTHANIDE COMPLEXES FOR USE AS LUMINESCENT MARKERS THE REGENTS OF THE UNIVERISTY OF CALIFORNIA (US) 2008-11-27 US disclosed
US-7404912-B2 Salicylamide-lanthanide complexes for use as luminescent markers THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-07-29 US disclosed
US-20060286567-A1 Salicylamide-lanthanide complexes for use as luminescent markers THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-12-21 US disclosed
US-7018850-B2 Salicylamide-lanthanide complexes for use as luminescent markers THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-03-28 US disclosed
EP-1154991-B1 SALICYLAMIDE-LANTHANIDE COMPLEXES FOR USE AS LUMINESCENT MARKERS UNIV CALIFORNIA (US) 2004-07-28 EP disclosed
US-20030027189-A1 Salicylamide-lanthanide complexes for use as luminescent markers THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2003-02-06 US disclosed
US-6406297-B1 USED FOR DETECTING AND QUANTIFYING CHEMICAL, BIOCHEMICAL AND BIOLOGICAL SUBSTANCES AS ANALYTES IN RESEARCH AND DIAGNOSTIC MIXTURES. THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2002-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060286567-A1 Salicylamide-lanthanide complexes for use as luminescent markers SCLY, SSB, LIG3 HPGD 1122/4885KDM4E 3308/4885TSHR 3100/4885
US-20030027189-A1 Salicylamide-lanthanide complexes for use as luminescent markers SCLY, SSB, LIG3 HPGD 1122/4885KDM4E 3308/4885TSHR 3100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.