Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 8/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.54 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.54 |
| ▸ | GRM3 | Q14832 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | GRM8 | O00222 | 2/20 | 0.54 |
| ▸ | GRM6 | O15303 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 1/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.54 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5007910 | 1.00 | GRM4 (0.54) | GRM4CYP1A2GRM2GRM3CYP2C19 | |
| SCHEMBL5007908 | 1.00 | GRM4 (0.54) | GRM4CYP1A2GRM2GRM3CYP2C19 | |
| 1-Aminocyclopropane Carboxylic Acid SCHEMBL28110484 | 0.92 | NSD2 (0.56) | GRM4CYP1A2GRM2GRM3CYP2C19 | |
| SCHEMBL10347256 | 0.84 | ARG1 (0.45) | GRM4CYP1A2GRM2GRM3CYP2C19 | |
| SCHEMBL18188079 | 0.80 | GRM4 (0.39) | GRM4CYP1A2GRM2GRM3CYP2C19 | |
| SCHEMBL544530 | 0.80 | GRM4 (0.54) | GRM4CYP1A2GRM2GRM3CYP2C19 | |
| SCHEMBL160783 | 0.80 | GRM4 (0.54) | GRM4CYP1A2GRM2GRM3CYP2C19 | |
| SCHEMBL912861 | 0.80 | GRM4 (0.54) | GRM4CYP1A2GRM2GRM3CYP2C19 | |
| SCHEMBL8535034 | 0.78 | GRM4 (0.52) | GRM4CYP1A2GRM2GRM3CYP2C19 | |
| SCHEMBL14372097 | 0.78 | GRM4 (0.52) | GRM4CYP1A2GRM2GRM3CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432302-B2 | Composition containing polyamine transport inhibitor and use thereof | MEDIQUEST THERAPEUTICS, INC. (US) | 2008-10-07 | — | — | US | disclosed |
| US-20050245615-A1 | Composition containing polyamine transport inhibitor and use thereof | MEDIQUEST THERAPEUTICS, INC. (US) | 2005-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245615-A1 | Composition containing polyamine transport inhibitor and use thereof | SLC7A1, SRM, SLC16A1 | GRM4 3939/4885CYP1A2 2431/4885GRM2 3234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.