Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.42 |
| ▸ | CTSG | P08311 | 4/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 4/20 | 0.42 |
| ▸ | CMA1 | P23946 | 4/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.39 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5008094 | 0.81 | POLB (0.51) | PRSS1CTSGCTRB1CMA1ALDH1A1 | |
| SCHEMBL1877455 | 0.77 | EPHX2 (0.48) | MEN1KMT2AEPHX2PRSS1CTSG | |
| SCHEMBL507273 | 0.76 | EPHX2 (0.55) | MEN1KMT2AEPHX2PRSS1CTSG | |
| SCHEMBL7837208 | 0.74 | CTSG (0.47) | MEN1KMT2AEPHX2PRSS1CTSG | |
| SCHEMBL7835765 | 0.73 | MEN1 (0.49) | MEN1KMT2AEPHX2PRSS1CTSG | |
| SCHEMBL7837709 | 0.73 | EPHX2 (0.47) | MEN1KMT2AEPHX2PRSS1CTSG | |
| SCHEMBL1877453 | 0.73 | POLB (0.64) | MEN1KMT2AEPHX2PRSS1CTSG | |
| SCHEMBL7835600 | 0.72 | CTSG (0.46) | MEN1KMT2AEPHX2PRSS1CTSG | |
| SCHEMBL7837405 | 0.71 | MEN1 (0.47) | MEN1KMT2AEPHX2PRSS1CTSG | |
| SCHEMBL7826783 | 0.71 | CTSG (0.47) | MEN1KMT2AEPHX2PRSS1CTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080319055-A1 | Cooling Compounds | GIVAUDAN SA (CH) | 2008-12-25 | — | — | US | disclosed |
| EP-1860960-A1 | COOLING COMPOUNDS | Givaudan SA (CH) | 2007-12-05 | — | — | EP | disclosed |
| WO-2006099762-A1 | COOLING COMPOUNDS | GIVAUDAN SA (CH) | 2006-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080319055-A1 | Cooling Compounds | TAS2R1, TAS2R43, TAS2R3 | MEN1 1388/4885KMT2A 2207/4885EPHX2 575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.