Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.46 |
| ▸ | CTSG | P08311 | 4/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 4/20 | 0.46 |
| ▸ | CMA1 | P23946 | 4/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7837208 | 0.90 | CTSG (0.47) | EPHX2MEN1KMT2APRSS1CTSG | |
| SCHEMBL7835600 | 0.87 | CTSG (0.46) | EPHX2MEN1KMT2APRSS1CTSG | |
| SCHEMBL7826783 | 0.86 | CTSG (0.47) | EPHX2MEN1KMT2APRSS1CTSG | |
| SCHEMBL7835765 | 0.82 | MEN1 (0.49) | EPHX2MEN1KMT2APRSS1CTSG | |
| SCHEMBL7836334 | 0.81 | NPC1 (0.49) | EPHX2MEN1KMT2APRSS1CTSG | |
| SCHEMBL7837405 | 0.80 | MEN1 (0.47) | EPHX2MEN1KMT2APRSS1CTSG | |
| SCHEMBL7825860 | 0.77 | PRSS1 (0.58) | EPHX2MEN1KMT2APRSS1CTSG | |
| SCHEMBL7825622 | 0.76 | NPC1 (0.46) | EPHX2MEN1KMT2APRSS1CTSG | |
| SCHEMBL507273 | 0.76 | EPHX2 (0.55) | EPHX2MEN1KMT2APRSS1CTSG | |
| SCHEMBL7837285 | 0.74 | EPHX2 (0.55) | EPHX2MEN1KMT2APRSS1CTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800516-B1 | FIBRINOGEN RECEPTOR ANTAGONISTS HAVING SUBSTITUTED (b)-AMINO ACID RESIDUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | NIPPON STEEL CORP (JP) | 2001-09-19 | — | — | EP | disclosed |
| US-5866592-A | Fibrinogen receptor antagonist and pharmaceutical compositions comprising the same | NIPPON STEEL CORPORATION (JP) | 1999-02-02 | — | — | US | disclosed |