Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.67 |
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | PGR | P06401 | 5/20 | 0.54 |
| ▸ | CA12 | O43570 | 6/20 | 0.52 |
| ▸ | CA9 | Q16790 | 6/20 | 0.52 |
| ▸ | CA1 | P00915 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | GLA | P06280 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | CASP1 | P29466 | 2/20 | 0.52 |
| ▸ | CASP7 | P55210 | 2/20 | 0.52 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11033273 | 0.84 | CA12 (0.59) | CYP19A1MAOAMAOBCA12CA9 | |
| SCHEMBL15842362 | 0.83 | PGR (0.77) | CYP19A1MAOAMAOBPGRCA12 | |
| Hydrogen Sulfide SCHEMBL6878722 | 0.82 | CA12 (0.57) | CYP19A1MAOAMAOBCA12CA9 | |
| SCHEMBL5008339 | 0.76 | CYP19A1 (0.51) | CYP19A1MAOAMAOBPGRCA12 | |
| SCHEMBL30022703 | 0.76 | CYP19A1 (0.59) | CYP19A1PGRCA12CA9CA1 | |
| SCHEMBL31676674 | 0.75 | CA12 (0.73) | CYP19A1PGRCA12CA9CA1 | |
| SCHEMBL875198 | 0.75 | CA12 (0.60) | PGRCA12CA9CA1ALDH1A1 | |
| SCHEMBL15842536 | 0.74 | CYP19A1 (0.59) | CYP19A1MAOBPGRCA12CA9 | |
| SCHEMBL28318294 | 0.73 | DYRK1A (0.46) | CYP19A1MAOAMAOBCA12ALDH1A1 | |
| Coumarin SCHEMBL28377687 | 0.72 | CA12 (0.77) | MAOAMAOBPGRCA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105272972-A | Benzoheterocyclic hexadiene derivative having anti-virus activity | SHANGHAI TANGRUN PHARMACEUTICALS CO LTD | 2016-01-27 | — | — | CN | disclosed |
| US-7439260-B2 | 7-(1,3-thiazol-2-YL)thio-coumarin derivatives and their use as leukotriene biosynthesis inhibitors | MERCK FORSST CANADA & CO. (CA) | 2008-10-21 | — | — | US | disclosed |
| US-20060116406-A1 | 7-(1,3-thiazol-2-yl)thio!-coumarin derivatives and their use as leukotriene biosynthesis inhibitors | GAREAU YVES | 2006-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116406-A1 | 7-(1,3-thiazol-2-yl)thio!-coumarin derivatives and their use as leukotriene biosynthesis inhibitors | LTC4S, LTA4H, CYSLTR1 | CYP19A1 727/4885MAOA 2648/4885MAOB 2936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.